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The New Paradigm of Immunity to Tuberculosis

Overview of attention for book
Cover of 'The New Paradigm of Immunity to Tuberculosis'

Table of Contents

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    Book Overview
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    Chapter 1 Epidemiology of Tuberculosis Immunology
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    Chapter 2 Host–Pathogen Specificity in Tuberculosis
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    Chapter 3 Genetic Determinants of Susceptibility to Mycobacterial Infections: IRF8, A New Kid on the Block
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    Chapter 4 Evolution of Mycobacterium tuberculosis
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    Chapter 5 Mycobacterium tuberculosis Genes Involved in Regulation of Host Cell Death
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    Chapter 6 Dying to Live: How the Death Modality of the Infected Macrophage Affects Immunity to Tuberculosis
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    Chapter 7 Cytokines in the Balance of Protection and Pathology During Mycobacterial Infections
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    Chapter 8 Antigen-Specific CD8+ T Cells and Protective Immunity to Tuberculosis
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    Chapter 9 Foxp3+ Regulatory T Cells in Tuberculosis
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    Chapter 10 CD1a, CD1b, and CD1c in Immunity Against Mycobacteria
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    Chapter 11 CD1d and Natural Killer T Cells in Immunity to Mycobacterium tuberculosis
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    Chapter 12 The Role of B Cells and Humoral Immunity in Mycobacterium tuberculosis Infection
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    Chapter 13 Looking within the zebrafish to understand the tuberculous granuloma.
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    Chapter 14 Immunization Strategies Against Pulmonary Tuberculosis: Considerations of T Cell Geography
Attention for Chapter 2: Host–Pathogen Specificity in Tuberculosis
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Citations

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Chapter title
Host–Pathogen Specificity in Tuberculosis
Chapter number 2
Book title
The New Paradigm of Immunity to Tuberculosis
Published in
Advances in experimental medicine and biology, January 2013
DOI 10.1007/978-1-4614-6111-1_2
Pubmed ID
23468102
Book ISBNs
978-1-4614-6110-4, 978-1-4614-6111-1
Authors

Tania Di Pietrantonio, Erwin Schurr

Editors

Maziar Divangahi

Abstract

The host response to mycobacterial infection including tuberculosis depends on genetically controlled host and bacterial factors and their interaction. A largely unknown aspect of this interaction is whether disease results from an additive and independent effect of host and pathogen or from specific host-pathogen combinations. The preferential association of specific mycobacterial strains with specific ethnic groups provided tentative evidence in favor of host-pathogen specificity in tuberculosis and is consistent with the hypothesis of host-mycobacterial co-adaptation. Substantial evidence for specificity has now been provided by animal models and human case-control association studies. These studies indicate that differences in the host response to infection are at least in part due to specific combinations of host genetic factors and genetic and phenotypic characteristics of the infecting mycobacterial strain.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 2%
United States 1 2%
Unknown 39 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 22%
Researcher 7 17%
Student > Master 5 12%
Student > Bachelor 4 10%
Student > Doctoral Student 2 5%
Other 6 15%
Unknown 8 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 17%
Medicine and Dentistry 6 15%
Immunology and Microbiology 5 12%
Nursing and Health Professions 5 12%
Biochemistry, Genetics and Molecular Biology 4 10%
Other 8 20%
Unknown 6 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 May 2013.
All research outputs
#20,194,150
of 22,711,242 outputs
Outputs from Advances in experimental medicine and biology
#3,941
of 4,907 outputs
Outputs of similar age
#248,752
of 280,736 outputs
Outputs of similar age from Advances in experimental medicine and biology
#137
of 169 outputs
Altmetric has tracked 22,711,242 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,907 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,736 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 169 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.

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