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Imaging Mass Spectrometry

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Cover of 'Imaging Mass Spectrometry'

Table of Contents

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    Book Overview
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    Chapter 1 “A Future Amalgamation Between the Scientist and the Clinician?”
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    Chapter 2 Fresh Frozen Versus Formalin-Fixed Paraffin Embedded for Mass Spectrometry Imaging
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    Chapter 3 Imaging MS of Rodent Ocular Tissues and the Optic Nerve
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    Chapter 4 MALDI-MSI of Lipids in Human Skin
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    Chapter 5 MALDI-MSI Analysis of Cytological Smears: The Study of Thyroid Cancer
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    Chapter 6 Droplet-Based Liquid Extraction for Spatially-Resolved Microproteomics Analysis of Tissue Sections
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    Chapter 7 DESI Mass Spectrometry Imaging (MSI)
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    Chapter 8 Peptide Imaging: Maximizing Peptide Yield, Optimization of the “Peptide Mass Fingerprint”
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    Chapter 9 MALDI-MS Imaging in the Study of Glomerulonephritis
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    Chapter 10 Hierarchical Cluster Analysis to Aid Diagnostic Image Data Visualization of MS and Other Medical Imaging Modalities
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    Chapter 11 Laser Ablation Inductively Coupled Plasma Mass Spectrometry Imaging of Plant Metabolites
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    Chapter 12 Mass Spectrometry Imaging of Drugs of Abuse in Hair
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    Chapter 13 MALDI Mass Spectrometry Profiling and Imaging Applied to the Analysis of Latent Fingermarks
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    Chapter 14 ToF-SIMS Parallel Imaging MS/MS of Lipid Species in Thin Tissue Sections
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    Chapter 15 Rodent Whole-Body Sectioning and MALDI Mass Spectrometry Imaging
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    Chapter 16 The Future in Disease Models for Mass Spectrometry Imaging, Ethical Issues, and the Way Forward
Attention for Chapter 2: Fresh Frozen Versus Formalin-Fixed Paraffin Embedded for Mass Spectrometry Imaging
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Chapter title
Fresh Frozen Versus Formalin-Fixed Paraffin Embedded for Mass Spectrometry Imaging
Chapter number 2
Book title
Imaging Mass Spectrometry
Published in
Methods in molecular biology, May 2017
DOI 10.1007/978-1-4939-7051-3_2
Pubmed ID
Book ISBNs
978-1-4939-7050-6, 978-1-4939-7051-3
Authors

Ekta Patel

Editors

Laura M. Cole

Abstract

Matrix-Assisted Laser Desorption Ionization (MALDI) Mass Spectrometry Imaging (MSI) is fast becoming an industry leading technique as a means of investigating the distributions of protein and peptide molecules directly from sections of tissue. Developing protocols for the analysis of FFPE tissue opens up numerous opportunities for novel biomarker discovery, due to the large number of tissue banks containing FFPE biopsy samples. This chapter reports the analysis of both fresh frozen and formalin-fixed paraffin-embedded (FFPE) tissues using such protocols.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 18%
Researcher 3 18%
Other 2 12%
Student > Bachelor 1 6%
Unspecified 1 6%
Other 2 12%
Unknown 5 29%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 29%
Unspecified 1 6%
Agricultural and Biological Sciences 1 6%
Immunology and Microbiology 1 6%
Chemistry 1 6%
Other 0 0%
Unknown 8 47%