Chapter title |
Registration of Pathological Images
|
---|---|
Chapter number | 10 |
Book title |
Simulation and Synthesis in Medical Imaging
|
Published in |
Lecture notes in computer science, September 2016
|
DOI | 10.1007/978-3-319-46630-9_10 |
Pubmed ID | |
Book ISBNs |
978-3-31-946629-3, 978-3-31-946630-9
|
Authors |
Xiao Yang, Xu Han, Eunbyung Park, Stephen Aylward, Roland Kwitt, Marc Niethammer |
Abstract |
This paper proposes an approach to improve atlas-to-image registration accuracy with large pathologies. Instead of directly registering an atlas to a pathological image, the method learns a mapping from the pathological image to a quasi-normal image, for which more accurate registration is possible. Specifically, the method uses a deep variational convolutional encoder-decoder network to learn the mapping. Furthermore, the method estimates local mapping uncertainty through network inference statistics and uses those estimates to down-weight the image registration similarity measure in areas of high uncertainty. The performance of the method is quantified using synthetic brain tumor images and images from the brain tumor segmentation challenge (BRATS 2015). |
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Geographical breakdown
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Unknown | 41 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 12 | 29% |
Student > Master | 6 | 15% |
Researcher | 5 | 12% |
Lecturer | 2 | 5% |
Student > Bachelor | 1 | 2% |
Other | 2 | 5% |
Unknown | 13 | 32% |
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Other | 2 | 5% |
Unknown | 16 | 39% |