Report for: Drug Targets in Kinetoplastid Parasites

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Chapter title	DNA Topoisomerases of Leishmania: The Potential Targets for Anti-Leishmanial Therapy
Chapter number	9
Book title	Drug Targets in Kinetoplastid Parasites
Published in	Advances in experimental medicine and biology, March 2008
DOI	10.1007/978-0-387-77570-8_9
Pubmed ID	18365662
Book ISBNs	978-0-387-77569-2, 978-0-387-77570-8
Authors	Das BB, Ganguly A, Majumder HK, Benu Brata Das, Agneyo Ganguly, Hemanta K. Majumder
Abstract	Protozoan parasites of the genus Leishmania cause severe diseases that threaten human beings, both for the high mortality rates involved and the economic loss resulting from morbidity, primarily in the tropical and subtropical areas. This ancient eukaryote shows variable genetic diversity in their life cycle, wherein DNA topoisomerases play a key role in cellular processes affecting the topology and organization ofintracellular DNA. Kinetoplastid topoisomerases offer most attractive targets for their structural diversity from other eukaryotic counterparts and their indispensable function in cell biology Therefore, understanding the biology of kinetoplastid topoisomerases and the components and steps involved in this intricate process provide opportunities for target based drug designing against protozoan parasitic diseases.

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Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country	Count	As %
Unknown	39	100%

Demographic breakdown

Readers by professional status	Count	As %
Student > Ph. D. Student	7	18%
Researcher	5	13%
Student > Master	5	13%
Professor > Associate Professor	4	10%
Student > Bachelor	3	8%
Other	12	31%
Unknown	3	8%

Readers by discipline	Count	As %
Medicine and Dentistry	7	18%
Agricultural and Biological Sciences	7	18%
Biochemistry, Genetics and Molecular Biology	5	13%
Chemistry	5	13%
Pharmacology, Toxicology and Pharmaceutical Science	2	5%
Other	5	13%
Unknown	8	21%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 October 2014.

All research outputs

#20,241,019

of 22,768,097 outputs

Outputs from Advances in experimental medicine and biology

#3,955

of 4,928 outputs

Outputs of similar age

#78,139

of 81,283 outputs

Outputs of similar age from Advances in experimental medicine and biology

of 5 outputs

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Drug Targets in Kinetoplastid Parasites

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Geographical breakdown

Demographic breakdown

Attention Score in Context