From Molecules to Medicines : Structure of Biological Macromolecules and Its Relevance in Combating New Diseases and Bioterrorism

Chapter 1 From Molecules to Medicines

Chapter 2 The Rapid Crystallization Strategy for Structure-Based Inhibitor Design

Chapter 3 Fragment-Based Drug Discovery in Academia: Experiences From a Tuberculosis Programme

Chapter 4 Structural Biology Contributions to the Discovery of Drugs to Treat Chronic Myelogenous Leukemia

Chapter 5 Integrating Crystallography into Early Metabolism Studies

Chapter 6 The Foundations of Protein–Ligand Interaction

Chapter 7 Structure-Based Design of Trna-Guanine Transglycosylase Inhibitors

Chapter 8 Progress on New Hepatitis C Virus Targets: NS2 and NS5A

Chapter 9 Protein Structure Modeling

Chapter 10 Structural Biology and Molecular Modeling in the Design of Novel DPP-4 Inhibitors

Chapter 11 Tools to Make 3D Structural Data More Comprehensible: Emovie & Proteopedia

Chapter 12 Structural Studies on Acetylcholinesterase and Paraoxonase Directed Towards Development of Therapeutic Biomolecules for the Treatment of Degenerative Diseases and Protection Against Chemical Threat Agents

Chapter 13 Protein Function Prediction from Structure in Structural Genomics and its Contribution to the Study of Health and Disease

Chapter 14 Crystal Structures of the β2-Adrenergic Receptor

Chapter 15 Can Structures Lead to Better Drugs? Lessons from Ribosome Research