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Cell Biology and Translational Medicine, Volume 21

Overview of attention for book
Cover of 'Cell Biology and Translational Medicine, Volume 21'

Table of Contents

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    Book Overview
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    Chapter 777 Secretome Analysis of Human Nasal Fibroblast Identifies Proteins That Promote Wound Healing
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    Chapter 778 An Insight into Vital Genes Responsible for β-cell Formation
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    Chapter 779 Extracellular Vesicles in Domestic Animals: Cellular Communication in Health and Disease
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    Chapter 780 Mesenchymal Stem Cells: A Promising Treatment for Thymic Involution.
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    Chapter 781 Regulation of Hepatocellular Carcinoma Epithelial-Mesenchymal Transition Mechanism and Targeted Therapeutic Approaches
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    Chapter 782 Combined Endurance and Strength or Only Endurance Training? Effects of Training Mode on Neuromuscular Characteristics and Functional Abilities in Obese Adolescent Girls Enrolled in a Weight-Reduction Program
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    Chapter 783 Sex-Related Neuromuscular Adaptations to Youth Obesity: Force, Muscle Mass, and Neural Issues
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    Chapter 784 Systemic Inflammation but not Oxidative Stress Is Associated with Physical Performance in Moderate Chronic Obstructive Pulmonary Disease
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    Chapter 785 Recellularization of Acellular Xeno Kidney Scaffold: An In Vivo Method to Generate Bioartificial Kidney
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    Chapter 788 The Application of Electromagnetic Fields in Cancer
Attention for Chapter 780: Mesenchymal Stem Cells: A Promising Treatment for Thymic Involution.
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (54th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

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Chapter title
Mesenchymal Stem Cells: A Promising Treatment for Thymic Involution.
Chapter number 780
Book title
Cell Biology and Translational Medicine, Volume 21
Published in
Advances in experimental medicine and biology, July 2023
DOI 10.1007/5584_2023_780
Pubmed ID
37421539
Book ISBNs
978-3-03-156831-2, 978-3-03-156832-9
Authors

Yang, Zailing, Peng, Yunxiao, Yuan, Jun, Xia, Haixiong, Luo, Li, Wu, Xijun, Zailing Yang, Yunxiao Peng, Jun Yuan, Haixiong Xia, Li Luo, Xijun Wu

Abstract

The thymus is the main immune organ in the body. However, the thymus gradually degenerates in early life, leading to a reduction in T-cell production and a decrease in immune function. Mesenchymal stem cells (MSCs) are a promising alternative for the treatment of thymus senescence due to their homing ability to the site of inflammation and their paracrine, anti-inflammatory, and antioxidant properties. However, the heterogeneity, difficulty of survival in vivo, short residence time, and low homing efficiency of the injected MSCs affect the clinical therapeutic effect. This article reviews strategies to improve the efficacy of mesenchymal stem cell therapy, including the selection of appropriate cell doses, transplantation frequency, and interval cycles. The survival rate of MSCs can be improved to some extent by improving the infusion mode of MSCs, such as simulating the in vivo environment, applying the biological technology of hydrogels and microgels, and iron oxide labeling technology, which can improve the curative effect and homing of MSCs, promote the regeneration of thymic epithelial cells, and restore the function of the thymus.

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 Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2024.
All research outputs
#15,035,227
of 25,173,778 outputs
Outputs from Advances in experimental medicine and biology
#2,073
of 5,271 outputs
Outputs of similar age
#155,211
of 352,037 outputs
Outputs of similar age from Advances in experimental medicine and biology
#15
of 114 outputs
Altmetric has tracked 25,173,778 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,271 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,037 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.
We're also able to compare this research output to 114 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.

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