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X Demographics
Attention Score in Context
| Chapter title |
GMP-Based Isolation of Full-Term Human Placenta-Derived NK Cells for CAR-NK Cell Therapy in Malignant Melanoma
|
|---|---|
| Book title |
Methods in Molecular Biology
|
| Published in |
Methods in molecular biology, October 2023
|
| DOI | 10.1007/7651_2023_503 |
| Pubmed ID | |
| Authors |
Roudsari, Peyvand Parhizkar, Alavi-Moghadam, Sepideh, Aghayan, Hamid Reza, Arjmand, Rasta, Gilany, Kambiz, Rezaei-Tavirani, Mostafa, Arjmand, Babak, Peyvand Parhizkar Roudsari, Sepideh Alavi-Moghadam, Hamid Reza Aghayan, Rasta Arjmand, Kambiz Gilany, Mostafa Rezaei-Tavirani, Babak Arjmand |
| Abstract |
Melanoma, a severe type of skin cancer, poses significant management challenges due to its resistance to available treatments. Despite this obstacle, the high immunogenicity of melanoma renders it amenable to immune therapy, and NK cells have been identified as possessing anti-tumor properties in immunotherapy. The development of chimeric antigen receptor (CAR)-modified NK cells, or CAR-NK cells, has shown potential in enhancing immunotherapeutic regimens. To achieve this, researchers have explored various sources of NK cells, including those derived from the placenta, which offers benefits compared to other sources due to their limited ex vivo expansion potential. Recent studies have indicated the capacity to expand functional NK cells from placenta-derived cells in vitro that possess anti-tumor cytolytic properties. This chapter discusses the isolation of full-term human placenta-derived NK cells using Good Manufacturing Practice-based methods for CAR-NK cell therapy in melanoma. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 October 2023.
All research outputs
#16,182,820
of 24,614,554 outputs
Outputs from Methods in molecular biology
#5,110
of 13,846 outputs
Outputs of similar age
#95,161
of 192,277 outputs
Outputs of similar age from Methods in molecular biology
#13
of 80 outputs
Altmetric has tracked 24,614,554 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,846 research outputs from this source. They receive a mean Attention Score of 3.5. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 192,277 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 80 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.