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DNA-Encoded Chemical Libraries

Overview of attention for book
Cover of 'DNA-Encoded Chemical Libraries'

Table of Contents

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    Book Overview
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    Chapter 1 Library Synthesis: Building Block Selection, Handling, and Tracking
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    Chapter 2 Library Synthesis: Building Block Validation
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    Chapter 3 Library Synthesis and Analytics
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    Chapter 4 Chemical Ligation of Oligonucleotide Tags to Support Encoded Chemical Library Synthesis
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    Chapter 5 On-DNA Reductive Amination and Alkylation
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    Chapter 6 On-DNA-1,2,3-Triazole Formation via Click Reaction
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    Chapter 7 On-DNA Suzuki-Miyaura Cross-Coupling
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    Chapter 8 On-DNA Pd and Cu-Promoted C-N Cross-Coupling Reactions
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    Chapter 9 Palladium-Promoted On-DNA Heck Reactions
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    Chapter 10 Ruthenium-Promoted On-DNA C-H Activation Reaction
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    Chapter 11 DNA-Compatible Nitro Reduction and Synthesis of Benzimidazoles
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    Chapter 12 Condensation of DNA-Conjugated Imines with Homophthalic Anhydride for the Synthesis of Isoquinolones On-DNA
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    Chapter 13 DNA Encoding of Natural Products
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    Chapter 14 Initiating DNA-Encoded Library Synthesis with a Hexathymidine DNA Oligonucleotide
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    Chapter 15 One Bead-One Compound (OBOC) Peptidomimetic-Encoded Library Synthesis via Split-and-Pool Methods
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    Chapter 16 DNA Conjugates as Tool Compounds for DEL Selections
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    Chapter 17 Quantitation of DNA-Encoded Libraries by qPCR
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    Chapter 18 Target Protein Design and Preselection Analysis
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    Chapter 19 DEL Selections Against a Soluble Protein Target
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    Chapter 20 Selection Method of DNA-Encoded Chemical Library for Irreversible Covalent Binders
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    Chapter 21 Next Generation Sequencing of DNA-Encoded Libraries
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    Chapter 22 Translation of DNA Sequence to Chemical Structure in DNA-Encoded Libraries
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    Chapter 23 Analysis of DNA-Encoded Library Screening Data: Selection of Molecules for Synthesis
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    Chapter 24 High-Throughput Binder Confirmation (HTBC)
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    Chapter 25 High-Throughput Binder Confirmation Using Affinity Selection Mass Spectrometry
Attention for Chapter 18: Target Protein Design and Preselection Analysis
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Chapter title
Target Protein Design and Preselection Analysis
Chapter number 18
Book title
DNA-Encoded Chemical Libraries
Published by
Humana, New York, NY, September 2022
DOI 10.1007/978-1-0716-2545-3_18
Pubmed ID
36083553
Book ISBNs
978-1-07-162544-6, 978-1-07-162545-3
Authors

Qiuxia Chen, David I. Israel, Chen, Qiuxia, Israel, David I.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 2 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 2 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 1 50%
Unknown 1 50%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 1 50%
Unknown 1 50%

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