Chemical Protein Synthesis

Chapter 1 Sulfated Glycoprotein Synthesis

Chapter 2 Total Chemical Synthesis of a SARS-CoV-2 Miniprotein Inhibitor LCB1

Chapter 3 Serine/Threonine Ligation and Cysteine/Penicillamine Ligation

Chapter 4 Continuous-Flow Synthesis of N-Methylated Peptides via Generation of an Acyl N-Methylimidazolium Cation

Chapter 5 Covalent Reactive Peptides to Block Protein–Protein Interactions and Inhibit Microbe–Host Interaction

Chapter 6 Ynamide-Mediated Synthetic Approach to Thioamide-Substituted Peptides

Chapter 7 Improved Handling of Peptide Segments Using Side Chain-Based “Helping Hand” Solubilizing Tools

Chapter 8 General Solution to the Preparation of β-Thiolated/Selenolated Amino Acids Via Visible Light Catalyzed Asymmetric Giese Reaction

Chapter 9 Side-Chain Anchoring Strategies for the Synthesis of Peptide Thioesters and Selenoesters

Chapter 10 Preparation of Site-Specific Succinylated Histone Mimics to Investigate Its Impact on Nucleosome Dynamics

Chapter 11 Protein Synthesis via Activated Cysteine-Directed Protein Ligation

Chapter 12 Sulfonium-Tethered Peptide

Chapter 13 PAL-Mediated Ligation for Protein and Cell-Surface Modification

Chapter 14 Development of a Glycoform Library-based Strategy to Decipher the Role of Protein Glycosylation

Chapter 15 A Selenium-based Cysteine Surrogate for Protein Chemical Synthesis

Chapter 16 Removable Backbone Modification (RBM) Strategy for the Chemical Synthesis of Hydrophobic Peptides/Proteins