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The ADME Encyclopedia

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Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 7 Drug Excretion
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    Chapter 12 Buccal Route of Drug Delivery
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    Chapter 15 Pulmonary Drug Delivery
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    Chapter 19 Biopharmaceutical Drug Products: An Overview of Physicochemical Properties and Their Modification
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    Chapter 21 Pharmacogenomics and Pediatrics
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    Chapter 29 Drug Dissolution: Fundamental Theoretic Models
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    Chapter 35 Korsmeyer-Peppas, Peppas-Sahlin, and Brazel-Peppas: Models of Drug Release
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    Chapter 37 Baker-Lonsdale Model of Drug Release
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    Chapter 43 Biorelevant Dissolution Media
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    Chapter 44 Free Diffusion in Drug Absorption
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    Chapter 51 Free Drug Theory
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    Chapter 52 Real and Apparent Volumes of Distribution
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    Chapter 57 Drug Binding to Tissue Components
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    Chapter 59 Two-Compartment Pharmacokinetic Model
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    Chapter 60 Central Nervous System Bioavailability
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    Chapter 61 Brain-to-Plasma Concentration Ratio and Unbound Partition Coefficient
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    Chapter 64 Drug Metabolism Synthetic (Phase II) Reactions
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    Chapter 65 Cytochrome P450
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    Chapter 69 Personalized Medicine and Drug Metabolism
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    Chapter 71 Biliary Drug Excretion
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    Chapter 72 Enterohepatic Recycling
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    Chapter 77 ABC Transporters: Drug Transfer Across Cellular Interfaces
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    Chapter 81 ABC Transporters: Individual-Specific Considerations
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    Chapter 84 Organic Anion Transporters and Organic Anion Transporting Polypeptides
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    Chapter 85 Organic Cation Transporters
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    Chapter 88 Plasma Protein Binding Drug Interactions
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    Chapter 90 Transporter Drug Interactions
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    Chapter 91 Oral Drug Delivery and Food-Drug Interactions
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    Chapter 92 Gastric Emptying
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    Chapter 94 Intestinal Perfusion Models
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    Chapter 95 Sublingual Route of Drug Delivery
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    Chapter 96 Intravenous Drug Delivery
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    Chapter 97 Intravenous Bolus and Infusion
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    Chapter 99 Intramuscular Drug Delivery
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    Chapter 100 Subcutaneous Drug Delivery
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    Chapter 103 Permeation Enhancers
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    Chapter 108 Passive Targeting and the Enhanced Permeability and Retention (EPR) Effect
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    Chapter 115 Nucleic Acids for Gene Therapy
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    Chapter 120 Biotechnology-Derived Biologics Drug Products: Elimination
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    Chapter 121 ADME Properties of Insulins
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    Chapter 124 Pharmacogenomics: Basis and Milestones
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    Chapter 125 Pharmacogenomics: Genetic Polymorphisms
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    Chapter 126 Pharmacokinetic Polymorphisms
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    Chapter 127 Pharmacodynamic Polymorphisms
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    Chapter 128 Pharmacogenomics: Challenges and Future Perspectives
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    Chapter 129 Bioavailability
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    Chapter 131 Bioequivalence Studies: Generic Products
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    Chapter 134 Bioavailability: Mass Balance Studies
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    Chapter 136 Bioequivalence Studies: Reference and Test Products
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    Chapter 143 Drug Solubility Assessment
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    Chapter 150 Central Nervous System Multiparameter Optimization Desirability
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    Chapter 151 Site of Metabolism Predictions
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    Chapter 152 Dynamic Transit Models
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    Chapter 154 Nonlinear Pharmacokinetics: Negative Deviation from Linearity
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    Chapter 155 Nonlinear Pharmacokinetics: Positive Deviation from Linearity
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    Chapter 156 Nonlinear Pharmacokinetic Responses in Variant Systems
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    Chapter 160 Chronobiology and Chronopharmacokinetics
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    Chapter 162 Chronopharmacokinetics: Aging and Sex
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    Chapter 163 Chronopharmacokinetics in the Clinics
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    Chapter 165 Physiologically Based Pharmacokinetic Modeling: Definition and History
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    Chapter 175 Pharmacometrics in Precision Dosing
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    Chapter 176 Noncompartmental Pharmacokinetics
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    Chapter 177 Stimuli-Responsive Nanocarriers for Drug Delivery
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    Chapter 178 Migrating Motor Complex
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    Chapter 300001 α1-Acid Glycoprotein
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    Chapter 300002 ABC20, PGY1
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    Chapter 300004 Absorption
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    Chapter 300007 Acid Dissociation Constant
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    Chapter 300008 Acid Dissociation Constant Determination
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    Chapter 300009 Acidic Dissociation Constant
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    Chapter 300017 ADME Structural Alerts
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    Chapter 300019 Albumin
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    Chapter 300024 BCRP
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    Chapter 300025 BDDCS
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    Chapter 300026 Biliary Drug Elimination
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    Chapter 300027 Biliary Excretion
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    Chapter 300028 Binding to Plasma Proteins
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    Chapter 300030 Biodistribution
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    Chapter 300032 Biological Variance
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    Chapter 300034 Biopharmaceutically Relevant Dissolution Media
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    Chapter 300036 Biorelevant Dissolution Technologies
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    Chapter 300039 Bolus
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    Chapter 300043 Brain-to-Plasma Ratio
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    Chapter 300045 Carrier-Mediated Transport
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    Chapter 300047 Central Bioavailability
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    Chapter 300049 Central Nervous System Drug Bioavailability
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    Chapter 300054 CNS Bioavailability
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    Chapter 300055 CNS Desirability Score
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    Chapter 300056 CNS Drug Bioavailability
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    Chapter 300057 CNS Multiparameter Optimization Desirability
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    Chapter 300060 Conjugation Reactions
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    Chapter 300061 Constant Rate Drug Release
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    Chapter 300062 Convection-Dispersion Model
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    Chapter 300064 CYP Phenotyping
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    Chapter 300069 CYP450 Phenotyping
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    Chapter 300070 CYP450 Testing
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    Chapter 300072 Cytochrome P450 (CYP)
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    Chapter 300084 Danckwerts Model
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    Chapter 300091 Dissolution Media
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    Chapter 300092 Dissolution Methods, Dissolution Apparatuses, Dissolution Tester, Experimental Setups for Dissolution Evaluation
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    Chapter 300093 Dissolution Test Media
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    Chapter 300094 Distribution Coefficient
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    Chapter 300097 DNA Microarrays
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    Chapter 300098 Double-Barrier Model
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    Chapter 300099 Drug Accumulation
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    Chapter 300103 Drug Delivery
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    Chapter 300107 Drug for Injection
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    Chapter 300110 Drug Metabolism and Pharmacokinetics (DMPK)
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    Chapter 300112 Drug Sequestration
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    Chapter 300114 Drug-Metabolizing Enzyme
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    Chapter 300116 Dynamic Models of Absorption
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    Chapter 300121 Enzyme Induction
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    Chapter 300122 Enzyme Inhibition
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    Chapter 300124 Ex Vivo Intestinal Perfusion
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    Chapter 300126 Exposure-Response Relationship
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    Chapter 300128 Fed State
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    Chapter 300129 Film Theory
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    Chapter 300131 Food Administration
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    Chapter 300133 Food-Drug Interactions
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    Chapter 300134 Fraction Bound
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    Chapter 300135 Fraction Unbound
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    Chapter 300137 Functionalization Metabolism
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    Chapter 300138 Functionalization Reactions
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    Chapter 300140 Gastrointestinal Motility
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    Chapter 300143 Gene Polymorphism
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    Chapter 300146 Generic Medicinal Products
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    Chapter 300148 Generic Products Evaluation
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    Chapter 300151 Genetic Science
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    Chapter 300155 Hepatic Clearance
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    Chapter 300156 Hepatobiliary Excretion
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    Chapter 300157 Higuchi, Baker and Lonsdale Model
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    Chapter 300159 Hot Spot Prediction
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    Chapter 300163 In Situ Intestinal Perfusion
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    Chapter 300165 Infusion
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    Chapter 300167 Injection
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    Chapter 300169 Injection into the Muscle
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    Chapter 300174 Intestinal Microorganisms
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    Chapter 300176 Intestinal Recirculating Perfusion
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    Chapter 300177 Intestinal Single-Pass Perfusion
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    Chapter 300178 Intra-abdominal Route
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    Chapter 300180 Intracisternal Route
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    Chapter 300182 Intradermic Administration
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    Chapter 300183 Intra-individual Variability
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    Chapter 300185 Intramuscular Administration
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    Chapter 300186 Intramuscular Delivery
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    Chapter 300187 Intramuscular Route
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    Chapter 300193 Intrathecal Route
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    Chapter 300194 Intravenous Pharmacokinetic
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    Chapter 300196 Intravenous Route Precautions
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    Chapter 300198 Intraventricular Route
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    Chapter 300200 Ionization Constant
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    Chapter 300203 IV Push
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    Chapter 300204 Kpuu
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    Chapter 300207 Liposomes
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    Chapter 300208 Liquid Chromatography (LC)
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    Chapter 300211 Mass Balance Studies
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    Chapter 300214 Meal Intake
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    Chapter 300218 Metabolic Clearance
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    Chapter 300219 Metabolically Liable Sites Prediction
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    Chapter 300222 Migrating Myoelectric Complex
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    Chapter 300223 Migratory Motor Complex
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    Chapter 300224 Migratory Myoelectric Complex
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    Chapter 300225 Mitoxantrone Resistance Protein, MXR, ABCP, ABC15
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    Chapter 300233 MRPs
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    Chapter 300235 Nanocarriers
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    Chapter 300236 Nanocrystals
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    Chapter 300238 Nanoparticles
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    Chapter 300242 Nanosystems
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    Chapter 300243 Neonatology
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    Chapter 300247 Nonlinear Binding to Plasma Proteins
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    Chapter 300252 Noyes-Whitney-Nernst-Brunner Model
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    Chapter 300255 OAT1
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    Chapter 300256 OAT10
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    Chapter 300257 OAT2
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    Chapter 300258 OAT3
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    Chapter 300261 OATP
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    Chapter 300262 OCT1
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    Chapter 300264 OCT3
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    Chapter 300266 OCTN2
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    Chapter 300268 One-Compartment Model
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    Chapter 300270 Oral Delivery
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    Chapter 300271 Oral Route
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    Chapter 300275 Organic Cation/Carnitine Transporters
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    Chapter 300279 Parenteral Infusion
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    Chapter 300283 Passive Absorption
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    Chapter 300284 PBPK
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    Chapter 300287 PBPK Absorption Modeling
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    Chapter 300288 PBPK Model
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    Chapter 300290 Pediatric Medicine
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    Chapter 300291 Pedology
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    Chapter 300295 Peppas-Sahlin Model
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    Chapter 300296 PepT1
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    Chapter 300301 Peptide Transporter 3
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    Chapter 300302 Peptide Transporter 4
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    Chapter 300305 Personalized Medicine
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    Chapter 300311 Pharmaceutical Nanocarrier Distribution and Elimination
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    Chapter 300313 Pharmacodynamics (PD)
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    Chapter 300315 Pharmacogenomic Testing
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    Chapter 300316 Pharmacokinetic Response to Drug Action
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    Chapter 300318 Pharmacokinetic Response to Drug Action Is Not Immediate
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    Chapter 300319 Pharmacokinetic Response to Drug Dosing
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    Chapter 300323 Pharmacokinetics (PK)
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    Chapter 300324 Pharmacokinetics Comparison
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    Chapter 300328 Phase 0 Reactions
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    Chapter 300331 Phase 1 Reactions
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    Chapter 300333 Phase 2 Metabolism
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    Chapter 300335 Phase 3 Metabolism
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    Chapter 300337 Phase 3 Transport
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    Chapter 300342 Phase II Reactions
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    Chapter 300343 Phase III Metabolism
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    Chapter 300345 Phase III Transport
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    Chapter 300347 Physiologically Based Absorption Modeling
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    Chapter 300348 PK/PD Modeling
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    Chapter 300350 PK-PD Modeling
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    Chapter 300353 Poor Metabolizers
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    Chapter 300354 Post-approval Changes
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    Chapter 300355 Post-approval Manufacturing Changes
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    Chapter 300356 POT
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    Chapter 300359 Precision Medicine
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    Chapter 300364 QSAR
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    Chapter 300367 Quantitative Structure-Activity Relationships
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    Chapter 300370 Quantitative Structure-Property Relationships
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    Chapter 300371 Rapid Metabolizer
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    Chapter 300372 Real Volume of Distribution
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    Chapter 300373 Rectal Drug Absorption
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    Chapter 300376 Rectal Route
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    Chapter 300377 Redox Reactions
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    Chapter 300379 Regioselectivty Prediction
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    Chapter 300383 Relationship Between Drug Exposure and Drug Effect
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    Chapter 300386 Renal Clearance
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    Chapter 300389 Renal Excretion
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    Chapter 300393 Self-Adhering Transdermal Drug Delivery Systems (TDS)
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    Chapter 300395 Skin Implant
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    Chapter 300397 SLC Superfamily
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    Chapter 300399 SLC21
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    Chapter 300400 SLC22A
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    Chapter 300404 Soft Spot Prediction
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    Chapter 300406 Solids to Reconstitute
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    Chapter 300407 Solute Carrier Transporters
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    Chapter 300408 SOM Prediction
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    Chapter 300411 Steady State Volume of Distribution
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    Chapter 300414 Sustained Drug Release
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    Chapter 300417 System Analysis Pharmacokinetics
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    Chapter 300418 Systemic Clearance
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    Chapter 300420 Therapeutic Equivalence
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    Chapter 300422 Thin-Film Diffusion Models
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    Chapter 300424 Total Clearance
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    Chapter 300427 Transdermal Patches
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    Chapter 300429 Ultra-rapid Metabolizers
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    Chapter 300431 Unbound Brain-to-Plasma Concentration Ratio
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    Chapter 300432 Unbound Brain-to-Plasma Ratio
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    Chapter 300434 Uptake
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    Chapter 300435 URAT1
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    Chapter 300438 Viral Gene Transfer
  256. Altmetric Badge
    Chapter 300440 Volume of Distribution
  257. Altmetric Badge
    Chapter 300441 Volume of Distribution Area
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Title
The ADME Encyclopedia
Published by
Springer International Publishing
DOI 10.1007/978-3-030-84860-6
ISBNs
978-3-03-084859-0, 978-3-03-084860-6
Editors

Talevi, Alan

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The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 2 17%
Professor 1 8%
Other 1 8%
Student > Bachelor 1 8%
Unknown 7 58%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 3 25%
Biochemistry, Genetics and Molecular Biology 1 8%
Chemistry 1 8%
Unknown 7 58%