Chapter title |
Epigenomic Profiling of Dorsal Root Ganglia upon Regenerative and Non-regenerative Axonal Injury.
|
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Chapter number | 7 |
Book title |
Axon Regeneration
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Published in |
Methods in molecular biology, January 2023
|
DOI | 10.1007/978-1-0716-3012-9_7 |
Pubmed ID | |
Book ISBNs |
978-1-07-163011-2, 978-1-07-163012-9
|
Authors |
Müller, Franziska, Chadwick, Jessica S, Di Giovanni, Simone, Palmisano, Ilaria, Chadwick, Jessica S., Franziska Müller, Jessica S. Chadwick, Simone Di Giovanni, Ilaria Palmisano, Giovanni, Simone |
Abstract |
RNA sequencing (RNA-seq), chromatin immunoprecipitation sequencing (ChIP-seq), and assay for transposase-accessible chromatin sequencing (ATAC-seq) are genome-wide techniques that provide information relative to gene expression, chromatin binding sites, and chromatin accessibility, respectively. Here we describe RNA-seq, H3K9ac, H3K27ac and H3K27me3 ChIP-seq, and ATAC-seq in dorsal root ganglia (DRG) after sciatic nerve or dorsal column axotomy, to characterize the transcriptional and epigenetic signatures of DRG upon regenerative vs non-regenerative axonal lesion. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |