| Chapter title |
MicroRNAs and Inflammation in Colorectal Cancer.
|
|---|---|
| Chapter number | 3 |
| Book title |
Non-coding RNAs in Colorectal Cancer
|
| Published in |
Advances in experimental medicine and biology, August 2016
|
| DOI | 10.1007/978-3-319-42059-2_3 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-942057-8, 978-3-31-942059-2
|
| Authors |
Claire Josse, Vincent Bours, Josse, Claire, Bours, Vincent |
| Editors |
Ondrej Slaby, George A. Calin |
| Abstract |
Colorectal cancers (CRC) are known to be related to inflammatory conditions, and inflammatory bowel diseases increase the relative risk for developing CRC. The use of anti-inflammatory drugs prevents the development of colorectal cancer.Several molecular mediators are connecting the pathways that are involved in inflammatory conditions and in carcinogenesis. By the way these pathways are tightly interwoven, with the consequence that a deregulation at the level of any of these molecular mediators can affect the others.MiRNAs are demonstrated to be deregulated in inflammatory bowel diseases and in colorectal cancer. Moreover, they target several molecular mediators that connect inflammation to cancer, and they are thus implicated in the route from inflammation to colorectal cancer.This chapter will focus on the miRNAs that are jointly deregulated in inflammatory bowel disease and in colorectal cancer. Their role on the regulation of the molecular mediators and pathways that link inflammation to cancer will be described. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 26 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 5 | 19% |
| Student > Master | 4 | 15% |
| Student > Ph. D. Student | 4 | 15% |
| Professor > Associate Professor | 3 | 12% |
| Student > Bachelor | 2 | 8% |
| Other | 5 | 19% |
| Unknown | 3 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 7 | 27% |
| Medicine and Dentistry | 6 | 23% |
| Agricultural and Biological Sciences | 3 | 12% |
| Nursing and Health Professions | 2 | 8% |
| Mathematics | 1 | 4% |
| Other | 2 | 8% |
| Unknown | 5 | 19% |