Chapter title |
The Zebrafish as a Model for Human Bacterial Infections.
|
---|---|
Chapter number | 16 |
Book title |
Bacterial Pathogenesis
|
Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-6673-8_16 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6671-4, 978-1-4939-6673-8
|
Authors |
Melody N. Neely |
Editors |
Pontus Nordenfelt, Mattias Collin |
Abstract |
The development of the zebrafish (Danio rerio) infectious disease model has provided new insights and information into pathogenesis. Many of these new discoveries would not have been possible using a typical mammalian model. The advantages of using this model are many and in the last 15 years the model has been exploited for the analysis of many different pathogens. Here, we describe in detail how to perform a bacterial infection using either the adult zebrafish or zebrafish larvae using microinjection. Multiple methods of analysis are described that can be used to address specific questions pertaining to disease progression and the interactions with the immune system. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Spain | 1 | 4% |
Unknown | 24 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Doctoral Student | 4 | 16% |
Student > Master | 4 | 16% |
Student > Ph. D. Student | 3 | 12% |
Student > Bachelor | 2 | 8% |
Lecturer | 2 | 8% |
Other | 2 | 8% |
Unknown | 8 | 32% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 4 | 16% |
Agricultural and Biological Sciences | 4 | 16% |
Immunology and Microbiology | 2 | 8% |
Medicine and Dentistry | 2 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Other | 2 | 8% |
Unknown | 10 | 40% |