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Cardiovascular Safety in Drug Development and Therapeutic Use

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Cover of 'Cardiovascular Safety in Drug Development and Therapeutic Use'

Table of Contents

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    Book Overview
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    Chapter 1 The Central Role of Cardiovascular Safety in Drug Development and Therapeutic Use
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    Chapter 2 Drug Structures and the Biological Basis of Drug Responses
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    Chapter 3 Cardiovascular Structure, Function, and Pathophysiology
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    Chapter 4 Analyzing and Reporting Efficacy Data
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    Chapter 5 Analyzing and Reporting Safety Data
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    Chapter 6 Meta-analysis, Group Sequential Study Designs, Centralized Endpoint Adjudication, and Composite Endpoints
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    Chapter 7 The Proarrhythmic Cardiac Safety Regulatory Landscape Circa 2005–2015: Drug-Induced hERG Channel Block and the Thorough QT/QTc Study
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    Chapter 8 QTc Exposure–Response Modeling as a Primary Methodology for Proarrhythmic Cardiac Safety Assessments
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    Chapter 9 The Comprehensive In Vitro Proarrhythmia Assay Initiative
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    Chapter 10 Oncology Drug Therapy: Cardiotoxicity and the Discipline of Cardio-oncology
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    Chapter 11 Blood Pressure Responses to Noncardiovascular Drugs in Development and Therapeutic Use
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    Chapter 12 The Genesis of Cardiovascular Safety Regulatory Landscapes for New Antidiabetic Drugs for Type 2 Diabetes
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    Chapter 13 Satisfying the Regulatory Requirements for New Antidiabetic Drugs for Type 2 Diabetes Most Expeditiously
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    Chapter 14 Postmarketing Cardiovascular Safety Considerations
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    Chapter 15 A Safety Perspective on Additional Aspects of Drug Development and Therapeutic Use
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Title
Cardiovascular Safety in Drug Development and Therapeutic Use
Published by
Springer International Publishing, January 2017
DOI 10.1007/978-3-319-40347-2
ISBNs
978-3-31-940345-8, 978-3-31-940347-2
Authors

Turner, J. Rick, Karnad, Dilip R., Kothari, Snehal, J. Rick Turner, Dilip R. Karnad, Snehal Kothari

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Sweden 1 1%
Unknown 88 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 11 12%
Student > Master 10 11%
Student > Ph. D. Student 10 11%
Researcher 5 6%
Student > Doctoral Student 4 4%
Other 11 12%
Unknown 38 43%
Readers by discipline Count As %
Nursing and Health Professions 13 15%
Medicine and Dentistry 12 13%
Biochemistry, Genetics and Molecular Biology 4 4%
Social Sciences 4 4%
Engineering 4 4%
Other 14 16%
Unknown 38 43%