Chapter 1 The Contribution of Microscopy to the Study of Alzheimer’s Disease, Amyloid Plaques and Aβ Fibrillogenesis

Chapter 2 Transgenic Mouse Models for APP Processing and Alzheimer’s Disease: Early and Late Defects

Chapter 4 β-Secretase, APP and Aβ in Alzheimer’s Disease

Chapter 5 The Non-Amyloidogenic Pathway: Structure and Function of α-Secretases

Chapter 6 Amyloid β Degradation: A Challenging Task for Brain Peptidases

Chapter 7 The Protective Role of Vitamin E in Vascular Amyloid β-Mediated Damage

Chapter 8 Amyloid Accumulation and Pathogensis of Alzheimer’s Disease: Significance of Monomeric, Oligomeric and Fibrillar Aβ

Chapter 9 Cholesterol and Amyloid β Fibrillogenesis

Chapter 10 Alzheimer’s β-Amyloid: Insights into Fibril Formation and Structure from Congo Red Binding

Chapter 11 The Aluminium-Amyloid Cascade Hypothesis and Alzheimer’s Disease

Chapter 12 Amyloid-β Metal Interaction and Metal Chelation

Chapter 13 The Interaction of Amyloid-β with ApoE

Chapter 14 Clusterin and Alzheimer’s Disease

Chapter 15 Acetylcholinesterase Interaction with Alzheimer Amyloid β

Chapter 16 Membrane Disordering Effects of β-Amyloid Peptides

Chapter 17 The Role of Alzheimer Aβ Peptides in Ion Transport Across Cell Membranes

Chapter 18 Amyloid Inhibitors and β-Sheet Breakers

Chapter 19 Cholesterol and Alzheimer’s Disease: Statins, Cholesterol Depletion in APP Processing and Aβ Generation

Chapter 20 Phosphorylated Amyloid-β: the Toxic Intermediate in Alzheimer’s Disease Neurodegeneration