Title |
Emu oil(s): A source of non-toxic transdermal anti-inflammatory agents in aboriginal medicine
|
---|---|
Published in |
Inflammopharmacology, March 1998
|
DOI | 10.1007/s10787-998-0001-9 |
Pubmed ID | |
Authors |
M. W. Whitehouse, A. G. Turner, C. K. C. Davis, M. S. Roberts |
Abstract |
The 'oil' obtained from emu fat can be a very effective inhibitor of chronic inflammation in rats when applied dermally (with a skin penetration enhancer). Assays for this activity using the adjuvant-induced arthritis model have shown: i. Considerable variability in potency of some commercial oil samples; ii. Little or no correlation of activity with colour or linolenic acid (18:3) content of the oil; iii. Relative stability of some active oils (to heat, ageing at room temperature); iv. The bulk of the anti-inflammatory activity was present in a low triglyceride fraction; and v. Potential arthritis-suppressant/immunoregulant activity of these active fractions. These studies point to the need for more rigid quality control before considering such a (now proven) traditional medicine as a complementary therapy.Repeated applications of selected oils did not induce any of the more prominent side-effects associated with NSAIDs (e.g. platelet inhibition, gastrotoxicity) or certain anti-arthritic drugs (proteinuria, leukopenia). |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Spain | 1 | 5% |
India | 1 | 5% |
Unknown | 20 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 5 | 23% |
Other | 2 | 9% |
Student > Doctoral Student | 2 | 9% |
Student > Bachelor | 2 | 9% |
Professor > Associate Professor | 2 | 9% |
Other | 3 | 14% |
Unknown | 6 | 27% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 4 | 18% |
Medicine and Dentistry | 3 | 14% |
Chemistry | 2 | 9% |
Nursing and Health Professions | 1 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Other | 4 | 18% |
Unknown | 7 | 32% |