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Recent Advances on Model Hosts

Overview of attention for book
Cover of 'Recent Advances on Model Hosts'

Table of Contents

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    Book Overview
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    Chapter 1 Amoeba provide insight into the origin of virulence in pathogenic fungi.
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    Chapter 2 Of Model Hosts and Man: Using Caenorhabditis elegans, Drosophila melanogaster and Galleria mellonella as Model Hosts for Infectious Disease Research.
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    Chapter 3 Caenorhabditis elegans as an Alternative Model to Study Senescence of Host Defense and the Prevention by Immunonutrition.
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    Chapter 4 Bacterial Effectors: Learning on the Fly
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    Chapter 5 A Drosophila asthma model - what the fly tells us about inflammatory diseases of the lung.
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    Chapter 6 Elucidating the In Vivo Targets of Photorhabdus Toxins in Real-Time Using Drosophila Embryos
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    Chapter 7 Ecological Niche Modeling as a Tool for Understanding Distributions and Interactions of Vectors, Hosts, and Etiologic Agents of Chagas Disease
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    Chapter 8 Where Simplicity Meets Complexity: Hydra , a Model for Host–Microbe Interactions
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    Chapter 9 Tick as a Model for the Study of a Primitive Complement System
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    Chapter 10 Models Hosts for the Study of Oral Candidiasis
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    Chapter 11 Creating a Pro-survival and Anti-inflammatory Phenotype by Modulation of Acetylation in Models of Hemorrhagic and Septic Shock
Attention for Chapter 2: Of Model Hosts and Man: Using Caenorhabditis elegans, Drosophila melanogaster and Galleria mellonella as Model Hosts for Infectious Disease Research.
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (79th percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

Mentioned by

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1 blog

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88 Mendeley
Summary Blogs
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Chapter title
Of Model Hosts and Man: Using Caenorhabditis elegans, Drosophila melanogaster and Galleria mellonella as Model Hosts for Infectious Disease Research.
Chapter number 2
Book title
Recent Advances on Model Hosts
Published in
Advances in experimental medicine and biology, December 2011
DOI 10.1007/978-1-4419-5638-5_2
Pubmed ID
22127881
Book ISBNs
978-1-4419-5637-8, 978-1-4419-5638-5
Authors

Glavis-Bloom J, Muhammed M, Mylonakis E, Justin Glavis-Bloom, Maged Muhammed, Eleftherios Mylonakis, Glavis-Bloom, Justin, Muhammed, Maged, Mylonakis, Eleftherios

Abstract

The use of invertebrate model hosts has increased in popularity due to numerous advantages of invertebrates over mammalian models, including ethical, logistical and budgetary features. This review provides an introduction to three model hosts, the nematode Caenorhabditis elegans, the fruit fly Drosophila melanogaster and the larvae of Galleria mellonella, the greater wax moth. It highlights principal experimental advantages of each model, for C. elegans the ability to run high-throughput assays, for D. melanogaster the evolutionarily conserved innate immune response, and for G. mellonella the ability to conduct experiments at 37°C and easily inoculate a precise quantity of pathogen. It additionally discusses recent research that has been conducted with each host to identify pathogen virulence factors, study the immune response, and evaluate potential antimicrobial compounds, focusing principally on fungal pathogens.

View on publisher site
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 87 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 20%
Student > Bachelor 13 15%
Researcher 11 13%
Student > Master 7 8%
Student > Doctoral Student 4 5%
Other 16 18%
Unknown 19 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 23 26%
Immunology and Microbiology 13 15%
Agricultural and Biological Sciences 12 14%
Veterinary Science and Veterinary Medicine 2 2%
Energy 2 2%
Other 15 17%
Unknown 21 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 April 2012.
All research outputs
#5,705,925
of 22,664,267 outputs
Outputs from Advances in experimental medicine and biology
#881
of 4,904 outputs
Outputs of similar age
#50,221
of 240,223 outputs
Outputs of similar age from Advances in experimental medicine and biology
#23
of 127 outputs
Altmetric has tracked 22,664,267 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 4,904 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,223 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 127 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.

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