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The Alkali Metal Ions: Their Role for Life

Overview of attention for book
Cover of 'The Alkali Metal Ions: Their Role for Life'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Bioinorganic Chemistry of the Alkali Metal Ions
  3. Altmetric Badge
    Chapter 2 The Alkali Metal Ions: Their Role for Life
  4. Altmetric Badge
    Chapter 3 The Alkali Metal Ions: Their Role for Life
  5. Altmetric Badge
    Chapter 4 Discriminating Properties of Alkali Metal Ions Towards the Constituents of Proteins and Nucleic Acids. Conclusions from Gas-Phase and Theoretical Studies
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    Chapter 5 Alkali Metal Ion Complexes with Phosphates, Nucleotides, Amino Acids, and Related Ligands of Biological Relevance. Their Properties in Solution
  7. Altmetric Badge
    Chapter 6 Sodium and Potassium Interactions with Nucleic Acids
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    Chapter 7 Role of Alkali Metal Ions in G-Quadruplex Nucleic Acid Structure and Stability
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    Chapter 8 Sodium and Potassium Ions in Proteins and Enzyme Catalysis
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    Chapter 9 Roles and Transport of Sodium and Potassium in Plants.
  11. Altmetric Badge
    Chapter 10 Potassium Versus Sodium Selectivity in Monovalent Ion Channel Selectivity Filters
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    Chapter 11 Sodium as Coupling Cation in Respiratory Energy Conversion
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    Chapter 12 The Alkali Metal Ions: Their Role for Life
  14. Altmetric Badge
    Chapter 13 Proton-Potassium (H + /K + ) ATPases: Properties and Roles in Health and Diseases
  15. Altmetric Badge
    Chapter 14 Bioinspired Artificial Sodium and Potassium Ion Channels
  16. Altmetric Badge
    Chapter 15 The Alkali Metal Ions: Their Role for Life
  17. Altmetric Badge
    Chapter 16 Sodium and Potassium Relating to Parkinson’s Disease and Traumatic Brain Injury
Attention for Chapter 7: Role of Alkali Metal Ions in G-Quadruplex Nucleic Acid Structure and Stability
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#13 of 133)
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

news
1 news outlet
wikipedia
3 Wikipedia pages

Citations

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46 Dimensions

Readers on

mendeley
118 Mendeley
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Chapter title
Role of Alkali Metal Ions in G-Quadruplex Nucleic Acid Structure and Stability
Chapter number 7
Book title
The Alkali Metal Ions: Their Role for Life
Published in
Metal ions in life sciences, January 2016
DOI 10.1007/978-3-319-21756-7_7
Pubmed ID
Book ISBNs
978-3-31-921755-0, 978-3-31-921756-7
Authors

Eric Largy, Jean-Louis Mergny, Valérie Gabelica, Largy, Eric, Mergny, Jean-Louis, Gabelica, Valérie

Abstract

G-quadruplexes are guanine-rich nucleic acids that fold by forming successive quartets of guanines (the G-tetrads), stabilized by intra-quartet hydrogen bonds, inter-quartet stacking, and cation coordination. This specific although highly polymorphic type of secondary structure deviates significantly from the classical B-DNA duplex. G-quadruplexes are detectable in human cells and are strongly suspected to be involved in a number of biological processes at the DNA and RNA levels. The vast structural polymorphism exhibited by G-quadruplexes, together with their putative biological relevance, makes them attractive therapeutic targets compared to canonical duplex DNA. This chapter focuses on the essential and specific coordination of alkali metal cations by G-quadruplex nucleic acids, and most notably on studies highlighting cation-dependent dissimilarities in their stability, structure, formation, and interconversion. Section 1 surveys G-quadruplex structures and their interactions with alkali metal ions while Section 2 presents analytical methods used to study G-quadruplexes. The influence of alkali cations on the stability, structure, and kinetics of formation of G-quadruplex structures of quadruplexes will be discussed in Sections 3 and 4. Section 5 focuses on the cation-induced interconversion of G-quadruplex structures. In Sections 3 to 5, we will particularly emphasize the comparisons between cations, most often K(+) and Na(+) because of their prevalence in the literature and in cells.

Mendeley readers

The data shown below were compiled from readership statistics for 118 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 118 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 27 23%
Student > Bachelor 18 15%
Researcher 15 13%
Student > Master 14 12%
Student > Doctoral Student 5 4%
Other 11 9%
Unknown 28 24%
Readers by discipline Count As %
Chemistry 33 28%
Biochemistry, Genetics and Molecular Biology 26 22%
Pharmacology, Toxicology and Pharmaceutical Science 8 7%
Immunology and Microbiology 3 3%
Physics and Astronomy 3 3%
Other 10 8%
Unknown 35 30%

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 April 2022.
All research outputs
#2,636,853
of 22,343,111 outputs
Outputs from Metal ions in life sciences
#13
of 133 outputs
Outputs of similar age
#51,845
of 409,006 outputs
Outputs of similar age from Metal ions in life sciences
#6
of 52 outputs
Altmetric has tracked 22,343,111 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 133 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 409,006 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 52 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.