Chapter title |
Minimum Information in In Vivo Research.
|
---|---|
Chapter number | 285 |
Book title |
Good Research Practice in Non-Clinical Pharmacology and Biomedicine
|
Published in |
Handbook of experimental pharmacology, September 2019
|
DOI | 10.1007/164_2019_285 |
Pubmed ID | |
Book ISBNs |
978-3-03-033655-4, 978-3-03-033656-1
|
Authors |
Patrizia Voehringer, Janet R. Nicholson |
Abstract |
Data quality, reproducibility and reliability are a matter of concern in many scientific fields including biomedical research. Robust, reproducible data and scientific rigour form the foundation on which future studies are built and determine the pace of knowledge gain and the time needed to develop new and innovative drugs that provide benefit to patients. Critical to the attainment of this is the precise and transparent reporting of data. In the current chapter, we will describe literature highlighting factors that constitute the minimum information that is needed to be included in the reporting of in vivo research. The main part of the chapter will focus on the minimum information that is essential for reporting in a scientific publication. In addition, we will present a table distinguishing information necessary to be recorded in a laboratory notebook or another form of internal protocols versus information that should be reported in a paper. We will use examples from the behavioural literature, in vivo studies where the use of anaesthetics and analgesics are used and finally ex vivo studies including histological evaluations and biochemical assays. |
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Finland | 1 | 100% |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Unknown | 11 | 100% |
Demographic breakdown
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Student > Ph. D. Student | 3 | 27% |
Researcher | 3 | 27% |
Student > Bachelor | 1 | 9% |
Other | 1 | 9% |
Unknown | 3 | 27% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 2 | 18% |
Engineering | 2 | 18% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 9% |
Agricultural and Biological Sciences | 1 | 9% |
Arts and Humanities | 1 | 9% |
Other | 0 | 0% |
Unknown | 4 | 36% |