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The Nociceptin/Orphanin FQ Peptide Receptor

Overview of attention for book
Cover of 'The Nociceptin/Orphanin FQ Peptide Receptor'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 182 Nociceptin/Orphanin FQ and Urinary Bladder
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    Chapter 185 The Nociceptin/Orphanin FQ System and the Regulation of Memory
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    Chapter 186 Therapeutic Approaches for NOP Receptor Antagonists in Neurobehavioral Disorders: Clinical Studies in Major Depressive Disorder and Alcohol Use Disorder with BTRX-246040 (LY2940094)
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    Chapter 188 NOP Ligands for the Treatment of Anxiety and Mood Disorders
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    Chapter 195 The History of N/OFQ and the NOP Receptor
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    Chapter 196 Regulation of the Genes Encoding the ppN/OFQ and NOP Receptor
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    Chapter 198 NOP-Targeted Peptide Ligands
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    Chapter 199 NOP Receptor Ligands and Parkinson’s Disease
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    Chapter 200 Pharmacological Assays for Investigating the NOP Receptor
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    Chapter 202 N/OFQ-NOP System and Airways
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    Chapter 203 N/OFQ-NOP System in Peripheral and Central Immunomodulation
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    Chapter 205 Electrophysiological Actions of N/OFQ
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    Chapter 206 Cebranopadol: A Novel First-in-Class Potent Analgesic Acting via NOP and Opioid Receptors
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    Chapter 209 NOP-Related Mechanisms in Substance Use Disorders
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    Chapter 211 Effects of NOP-Related Ligands in Nonhuman Primates
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    Chapter 212 N/OFQ-NOP System in Food Intake
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    Chapter 213 NOP-Targeted Nonpeptide Ligands
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    Chapter 214 NOP-Related Mechanisms in Pain and Analgesia
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    Chapter 215 NOP Receptor Signaling Cascades.
  21. Altmetric Badge
    Chapter 240 Correction to: Electrophysiological Actions of N/OFQ
Attention for Chapter 215: NOP Receptor Signaling Cascades.
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Chapter title
NOP Receptor Signaling Cascades.
Chapter number 215
Book title
The Nociceptin/Orphanin FQ Peptide Receptor
Published in
Handbook of experimental pharmacology, May 2019
DOI 10.1007/164_2019_215
Pubmed ID
Book ISBNs
978-3-03-020185-2, 978-3-03-020186-9
Authors

Parker, Kyle E, Bruchas, Michael R, Kyle E. Parker, Michael R. Bruchas, Parker, Kyle E., Bruchas, Michael R.

Abstract

The nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor is a G protein-coupled receptor with wide distribution throughout the peripheral and central nervous system. Similar to other opioid receptors, NOP receptors couple to intracellular second messengers and regulatory proteins to affect biological systems. In this chapter, we review the current literature for NOP signaling cascades including their role as classic GPCRs, the investigation of their kinase and arrestin signaling pathways, and the importance of examining biased signaling to critically evaluate the therapeutic potential of novel NOP agonists.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 7 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 43%
Student > Bachelor 2 29%
Unspecified 1 14%
Unknown 1 14%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 2 29%
Neuroscience 2 29%
Immunology and Microbiology 1 14%
Biochemistry, Genetics and Molecular Biology 1 14%
Unknown 1 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2019.
All research outputs
#18,681,024
of 23,146,350 outputs
Outputs from Handbook of experimental pharmacology
#507
of 650 outputs
Outputs of similar age
#263,464
of 351,369 outputs
Outputs of similar age from Handbook of experimental pharmacology
#5
of 6 outputs
Altmetric has tracked 23,146,350 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 650 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
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We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.