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Proteomics for Biomarker Discovery

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Cover of 'Proteomics for Biomarker Discovery'

Table of Contents

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    Book Overview
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    Chapter 1 Pre- and Post-analytical Factors in Biomarker Discovery
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    Chapter 2 Pre-fractionation of Noncirculating Biological Fluids to Improve Discovery of Clinically Relevant Protein Biomarkers
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    Chapter 3 Serum Exosome Isolation by Size-Exclusion Chromatography for the Discovery and Validation of Preeclampsia-Associated Biomarkers
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    Chapter 4 Protein Biomarker Discovery Using Human Blood Plasma Microparticles
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    Chapter 5 A Standardized and Reproducible Proteomics Protocol for Bottom-Up Quantitative Analysis of Protein Samples Using SP3 and Mass Spectrometry
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    Chapter 6 Analyzing Cerebrospinal Fluid Proteomes to Characterize Central Nervous System Disorders: A Highly Automated Mass Spectrometry-Based Pipeline for Biomarker Discovery
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    Chapter 7 Lys-C/Trypsin Tandem-Digestion Protocol for Gel-Free Proteomic Analysis of Colon Biopsies
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    Chapter 8 Tube-Gel: A Fast and Effective Sample Preparation Method for High-Throughput Quantitative Proteomics
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    Chapter 9 Protein Biomarker Discovery in Non-depleted Serum by Spectral Library-Based Data-Independent Acquisition Mass Spectrometry
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    Chapter 10 Discovering Protein Biomarkers from Clinical Peripheral Blood Mononuclear Cells Using Data-Independent Acquisition Mass Spectrometry
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    Chapter 11 Intact Protein Analysis by LC-MS for Characterizing Biomarkers in Cerebrospinal Fluid
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    Chapter 12 Detection of Proteoforms Using Top-Down Mass Spectrometry and Diagnostic Ions
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    Chapter 13 Development of a Highly Multiplexed SRM Assay for Biomarker Discovery in Formalin-Fixed Paraffin-Embedded Tissues
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    Chapter 14 Development and Validation of Multiple Reaction Monitoring (MRM) Assays for Clinical Applications
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    Chapter 15 Protein-Level Statistical Analysis of Quantitative Label-Free Proteomics Data with ProStaR
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    Chapter 16 Computation and Selection of Optimal Biomarker Combinations by Integrative ROC Analysis Using CombiROC
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    Chapter 17 PanelomiX for the Combination of Biomarkers
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    Chapter 18 Designing an In Silico Strategy to Select Tissue-Leakage Biomarkers Using the Galaxy Framework
Attention for Chapter 12: Detection of Proteoforms Using Top-Down Mass Spectrometry and Diagnostic Ions
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