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Mendeley readers
Attention Score in Context
Chapter title |
Advanced Assay Monitoring APP-Carboxyl-Terminal Fragments as Markers of APP Processing in Alzheimer Disease Mouse Models.
|
---|---|
Chapter number | 5 |
Book title |
Systems Biology of Alzheimer's Disease
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Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-2627-5_5 |
Pubmed ID | |
Book ISBNs |
978-1-4939-2626-8, 978-1-4939-2627-5
|
Authors |
García-Osta, Ana, Cuadrado-Tejedor, Mar, Ana García-Osta Ph.D., Mar Cuadrado-Tejedor, Ana García-Osta |
Editors |
Juan I. Castrillo, Stephen G. Oliver |
Abstract |
The 99-amino-acid-long APP-carboxy-terminal fragment, named C99, is a membrane-bound peptide generated from the amyloid precursor protein (APP) by β-secretase cleavage and is the direct precursor of amyloid beta (Aβ). Here we describe a method for the quantification of C99. The amount of C99 is an indicative value of the amyloid pathology in an Alzheimer's disease (AD) model, and could be used as a marker to study AD progression in comprehensive experiments, including screening for new compounds and repurposing of drugs to treat AD. |
Mendeley readers
The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 11 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 2 | 18% |
Student > Ph. D. Student | 1 | 9% |
Professor > Associate Professor | 1 | 9% |
Researcher | 1 | 9% |
Unknown | 6 | 55% |
Readers by discipline | Count | As % |
---|---|---|
Neuroscience | 3 | 27% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 9% |
Agricultural and Biological Sciences | 1 | 9% |
Medicine and Dentistry | 1 | 9% |
Unknown | 5 | 45% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 August 2015.
All research outputs
#4,177,584
of 22,821,814 outputs
Outputs from Methods in molecular biology
#1,132
of 13,124 outputs
Outputs of similar age
#71,805
of 393,507 outputs
Outputs of similar age from Methods in molecular biology
#168
of 1,470 outputs
Altmetric has tracked 22,821,814 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,124 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 393,507 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 1,470 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.