Prenatal Diagnosis

Chapter 1 Traditional Prenatal Diagnosis: Past to Present

Chapter 2 Overview of Preimplantation Genetic Diagnosis (PGD): Historical Perspective and Future Direction

Chapter 3 Noninvasive Approaches to Prenatal Diagnosis: Historical Perspective and Future Directions

Chapter 4 Molecular Testing for Preimplantation Genetic Diagnosis of Single Gene Disorders

Chapter 5 Detection of Aneuploidy and Unbalanced Rearrangements Using Comparative Genomic Hybridization Microarrays

Chapter 6 Aneuploidy Screening using Next Generation Sequencing

Chapter 7 DNA Extraction from Various Types of Prenatal Specimens

Chapter 8 Assessment of Maternal Cell Contamination in Prenatal Samples by Quantitative Fluorescent PCR (QF-PCR)

Chapter 9 Rapid Prenatal Aneuploidy Screening by Fluorescence In Situ Hybridization (FISH)

Chapter 10 Prenatal Detection of Chromosome Aneuploidy by Quantitative Fluorescence PCR

Chapter 11 Multiplex Ligation-Dependent Probe Amplification (MLPA) for Prenatal Diagnosis of Common Aneuploidies

Chapter 12 Chromosomal Microarray Analysis Using Array Comparative Genomic Hybridization on DNA from Amniotic Fluid and Chorionic Villus Sampling

Chapter 13 Prenatal Diagnosis Using Chromosomal SNP Microarrays

Chapter 14 Rapid Detection of Fetal Mendelian Disorders: Thalassemia and Sickle Cell Syndromes

Chapter 15 Prenatal Diagnosis of Cystic Fibrosis

Chapter 16 Prenatal Diagnosis of Tay-Sachs Disease

Chapter 17 Next Generation Sequencing of Prenatal Structural Chromosomal Rearrangements Using Large-Insert Libraries

Chapter 18 Prenatal Diagnosis by Whole Exome Sequencing in Fetuses with Ultrasound Abnormalities

Chapter 19 Isolation and Characterization of Amniotic Fluid-Derived Extracellular Vesicles for Biomarker Discovery

Chapter 20 Quad Screen Test, A Multiplexed Biomarker Assay for Prenatal Screening to Assess Birth Defects: The Columbia University Experience Using the Beckman Access2 Immunoassay Analyzer and Benetech PRA

Chapter 22 Noninvasive Detection of Fetal Aneuploidy Using Next Generation Sequencing

Chapter 23 Noninvasive Antenatal Screening for Fetal RHD in RhD Negative Women to Guide Targeted Anti-D Prophylaxis