| Chapter title |
Carbapenem-Resistant Klebsiella pneumoniae: Results of a Laboratory Surveillance Program in an Italian General Hospital (August 2014-January 2015) : Surveillance of Carbapenem-resistant Klebsiella pneumoniae.
|
|---|---|
| Chapter number | 5018 |
| Book title |
Advances in Microbiology, Infectious Diseases and Public Health
|
| Published in |
Advances in experimental medicine and biology, January 2016
|
| DOI | 10.1007/5584_2015_5018 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-927934-3, 978-3-31-927935-0
|
| Authors |
Monari, Claudia, Merlini, Luca, Nardelli, Emanuela, Cacioni, Maria, Repetto, Antonella, Mencacci, Antonella, Vecchiarelli, Anna, Claudia Monari, Luca Merlini, Emanuela Nardelli, Maria Cacioni, Antonella Repetto, Antonella Mencacci, Anna Vecchiarelli |
| Abstract |
In this study we report the analysis of 131 Klebsiella pneumoniae (K. pneumoniae) clinical isolates from patients hospitalized in various wards, of Perugia General Hospital, from August 2014 to January 2015. Forty two isolates (32.1 %), were resistant to at least one carbapenem antibiotic and, among these isolates, 14 (33.3 %) exhibited resistance to colistin. All isolates were carbapenemases producers and 41 (97.6 %) harboured the bla KPC gene. Carbapenem-resistant K. pneumoniae isolates (CRKPs) were, also, typed for the genotypic diversity and the results revealed the circulation of two major clusters.This surveillance study evidences the spread of CRKP isolates in Perugia General Hospital and confirms that carbapenem-resistant K. pneumoniae isolates have reached epidemic dissemination in Italy. In addition the percentage of resistance to colistin resulted to be less than that observed in other hospital laboratories across Italy. In conclusion the circulation of these isolates should be monitored and appropriate policy of surveillance must be used, in a target manner, in order to reduce the spread of carbapenem-resistant isolates. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 25% |
| Australia | 1 | 25% |
| United Kingdom | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 3% |
| Unknown | 28 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 5 | 17% |
| Student > Master | 5 | 17% |
| Student > Bachelor | 3 | 10% |
| Student > Postgraduate | 3 | 10% |
| Unspecified | 3 | 10% |
| Other | 4 | 14% |
| Unknown | 6 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 7 | 24% |
| Immunology and Microbiology | 5 | 17% |
| Unspecified | 3 | 10% |
| Agricultural and Biological Sciences | 3 | 10% |
| Environmental Science | 1 | 3% |
| Other | 2 | 7% |
| Unknown | 8 | 28% |