Chapter title |
Treatment of HIV for the Prevention of Transmission in Discordant Couples and at the Population Level
|
---|---|
Chapter number | 6 |
Book title |
HIV Vaccines and Cure
|
Published in |
Advances in experimental medicine and biology, January 2018
|
DOI | 10.1007/978-981-13-0484-2_6 |
Pubmed ID | |
Book ISBNs |
978-9-81-130483-5, 978-9-81-130484-2
|
Authors |
M. Kumi Smith, Britta L. Jewell, Timothy B. Hallett, Myron S. Cohen, Kumi Smith, M., Jewell, Britta L., Hallett, Timothy B., Cohen, Myron S. |
Abstract |
The scientific breakthrough proving that antiretroviral therapy (ART) can halt heterosexual HIV transmission came in the form of a landmark clinical trial conducted among serodiscordant couples. Study findings immediately informed global recommendations for the use of treatment as prevention in serodiscordant couples. The extent to which these findings are generalizable to other key populations or to groups exposed to HIV through nonsexual transmission routes (i.e., anal intercourse or unsafe injection of drugs) has since driven a large body of research. This review explores the history of HIV research in serodiscordant couples, the implications for management of couples, subsequent research on treatment as prevention in other key populations, and challenges in community implementation of these strategies. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 120 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 21 | 18% |
Student > Master | 15 | 13% |
Researcher | 11 | 9% |
Student > Ph. D. Student | 11 | 9% |
Student > Doctoral Student | 4 | 3% |
Other | 13 | 11% |
Unknown | 45 | 38% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 28 | 23% |
Nursing and Health Professions | 9 | 8% |
Biochemistry, Genetics and Molecular Biology | 7 | 6% |
Immunology and Microbiology | 5 | 4% |
Psychology | 5 | 4% |
Other | 15 | 13% |
Unknown | 51 | 43% |