Chapter title |
Genetic Aspects of Cell Line Development from a Synthetic Biology Perspective.
|
---|---|
Chapter number | 117 |
Book title |
Genomics and Systems Biology of Mammalian Cell Culture
|
Published in |
Advances in biochemical engineering biotechnology, November 2011
|
DOI | 10.1007/10_2011_117 |
Pubmed ID | |
Book ISBNs |
978-3-64-228349-9, 978-3-64-228350-5
|
Authors |
L. Botezatu, S. Sievers, L. Gama-Norton, R. Schucht, H. Hauser, D. Wirth, Botezatu, L., Sievers, S., Gama-Norton, L., Schucht, R., Hauser, H., Wirth, D. |
Abstract |
Animal cells can be regarded as factories for the production of relevant proteins. The advances described in this chapter towards the development of cell lines with higher productivity capacities, certain metabolic and proliferation properties, reduced apoptosis and other features must be regarded in an integrative perspective. The systematic application of systems biology approaches in combination with a synthetic arsenal for targeted modification of endogenous networks are proposed to lead towards the achievement of a predictable and technologically advanced cell system with high biotechnological impact. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 2% |
Unknown | 60 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 15 | 25% |
Researcher | 11 | 18% |
Student > Master | 9 | 15% |
Student > Bachelor | 7 | 11% |
Other | 7 | 11% |
Other | 6 | 10% |
Unknown | 6 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 14 | 23% |
Agricultural and Biological Sciences | 13 | 21% |
Chemical Engineering | 6 | 10% |
Engineering | 6 | 10% |
Social Sciences | 3 | 5% |
Other | 12 | 20% |
Unknown | 7 | 11% |