Lung Innate Immunity and Inflammation
Springer New York
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Timeline
Mendeley readers
| Chapter title |
Mouse Models of Acute Lung Injury and ARDS
|
|---|---|
| Chapter number | 22 |
| Book title |
Lung Innate Immunity and Inflammation
|
| Published in |
Methods in molecular biology, January 2018
|
| DOI | 10.1007/978-1-4939-8570-8_22 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-8569-2, 978-1-4939-8570-8
|
| Authors |
Franco R. D’Alessio, D’Alessio, Franco R. |
| Abstract |
The acute respiratory distress syndrome (ARDS) is a devastating illness characterized by severe hypoxemia and diffuse alveolar damage. Direct lung infection is the leading cause of ARDS and can be modeled in mice using sterile models of inflammation or live pathogens. In this chapter, two mouse models for ARDS are defined. These include an infectious model of ARDS driven by direct administration of Streptococcus pneumoniae and a sterile inflammatory model mediated by intratracheal administration of lipopolysaccharide. Methods for growth and preparation of Streptococcus pneumoniae are provided as methods to assess lung inflammation and injury. |
Mendeley readers
The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 111 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 18 | 16% |
| Student > Ph. D. Student | 16 | 14% |
| Student > Master | 12 | 11% |
| Student > Bachelor | 10 | 9% |
| Other | 6 | 5% |
| Other | 14 | 13% |
| Unknown | 35 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 15% |
| Biochemistry, Genetics and Molecular Biology | 15 | 14% |
| Immunology and Microbiology | 12 | 11% |
| Agricultural and Biological Sciences | 11 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 5% |
| Other | 7 | 6% |
| Unknown | 43 | 39% |