Chapter title |
Insights into the Phenotypic and Behavioral Effects of Teratogenic Drugs in Caenorhabditis elegans
|
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Chapter number | 11 |
Book title |
Teratogenicity Testing
|
Published in |
Methods in molecular biology, January 2018
|
DOI | 10.1007/978-1-4939-7883-0_11 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7882-3, 978-1-4939-7883-0
|
Authors |
Caralina Marín de Evsikova, Marín de Evsikova, Caralina |
Abstract |
Environmental toxicants, chemical substances produced or introduced into the environment directly by humans or their activities, can act as teratogens during development that negatively impact health. Long-term ramifications of environmental exposures to sublethal doses of teratogens are often unrecognized and unknown. The round worm, Caenorhabditis elegans, is an emerging model organism to investigate the long-term impacts of environmental teratogens upon health. This chapter describes a toxicant exposure paradigm integrated with phenotyping assays to screen adult worms, and their progeny, for effects on reproduction, growth and development, behavior, and energy balance. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 25% |
Unknown | 6 | 75% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 75% |
Scientists | 2 | 25% |