Chapter title |
The Emerging Roles of microRNAs in Stem Cell Aging
|
---|---|
Chapter number | 2 |
Book title |
Exosomes, Stem Cells and MicroRNA
|
Published in |
Advances in experimental medicine and biology, January 2018
|
DOI | 10.1007/978-3-319-74470-4_2 |
Pubmed ID | |
Book ISBNs |
978-3-31-974469-8, 978-3-31-974470-4
|
Authors |
Catharine Dietrich, Manish Singh, Nishant Kumar, Shree Ram Singh, Dietrich, Catharine, Singh, Manish, Kumar, Nishant, Singh, Shree Ram |
Abstract |
Aging is the continuous loss of tissue and organ function over time. MicroRNAs (miRNAs) are thought to play a vital role in this process. miRNAs are endogenous small noncoding RNAs that control the expression of target mRNA. They are involved in many biological processes such as developmental timing, differentiation, cell death, stem cell proliferation and differentiation, immune response, aging and cancer. Accumulating studies in recent years suggest that miRNAs play crucial roles in stem cell division and differentiation. In the present chapter, we present a brief overview of these studies and discuss their contributions toward our understanding of the importance of miRNAs in normal and aged stem cell function in various model systems. |
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Mendeley readers
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Researcher | 4 | 19% |
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Other | 0 | 0% |
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