Chapter 24 Avoiding PXR and CAR Activation and CYP3A4 Enzyme Induction

Chapter 25 Tactics to Avoid Inhibition of Cytochrome P450s

Chapter 29 The Influence of Bioisosteres in Drug Design: Tactical Applications to Address Developability Problems

Chapter 30 Strategies for Minimisation of the Cholestatic Liver Injury Liability Posed by Drug-Induced Bile Salt Export Pump (BSEP) Inhibition

Chapter 32 Improving Solubility via Structural Modification

Chapter 34 Drug-Induced Phospholipidosis: Prediction, Detection, and Mitigation Strategies

Chapter 35 Physical Properties in Drug Design

Chapter 38 Drug Discovery vs hERG

Chapter 71 Erratum to: Improving Solubility via Structural Modification

Chapter 72 Erratum to: Drug Discovery vs hERG

Chapter 73 Erratum to: Drug-Induced Phospholipidosis: Prediction, Detection, and Mitigation Strategies

Chapter 74 Erratum to: The Influence of Bioisosteres in Drug Design: Tactical Applications to Address Developability Problems