Chapter title |
Neural Targets in the Study and Treatment of Social Cognition in Autism Spectrum Disorder
|
---|---|
Chapter number | 11 |
Book title |
Cognitive Enhancement
|
Published in |
Handbook of experimental pharmacology, November 2015
|
DOI | 10.1007/978-3-319-16522-6_11 |
Pubmed ID | |
Book ISBNs |
978-3-31-916521-9, 978-3-31-916522-6
|
Authors |
Arshya Vahabzadeh, Samantha M. Landino, Beate C. Finger, William A. Carlezon Jr., Christopher J. McDougle, William A. Carlezon |
Abstract |
The purpose of this chapter is to present results from recent research on social cognition in autism spectrum disorder (ASD). The clinical phenomenology and neuroanatomical circuitry of ASD are first briefly described. The neuropharmacology of social cognition in animal models of ASD and humans is then addressed. Next, preclinical and clinical research on the neurohormone oxytocin is reviewed. This is followed by a presentation of results from preclinical and clinical studies on the excitatory amino acid glutamate. Finally, the role of neuroinflammation in ASD is addressed from the perspectives of preclinical neuroscience and research involving humans with ASD. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 83 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 15 | 18% |
Student > Doctoral Student | 9 | 11% |
Researcher | 9 | 11% |
Student > Master | 9 | 11% |
Student > Ph. D. Student | 6 | 7% |
Other | 12 | 14% |
Unknown | 23 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 18 | 22% |
Psychology | 16 | 19% |
Neuroscience | 8 | 10% |
Agricultural and Biological Sciences | 6 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
Other | 5 | 6% |
Unknown | 28 | 34% |