Chapter title |
Interaction of Stress, Corticotropin-Releasing Factor, Arginine Vasopressin and Behaviour
|
---|---|
Chapter number | 306 |
Book title |
Behavioral Neurobiology of Stress-related Disorders
|
Published in |
Current topics in behavioral neurosciences, March 2014
|
DOI | 10.1007/7854_2014_306 |
Pubmed ID | |
Book ISBNs |
978-3-66-245125-0, 978-3-66-245126-7
|
Authors |
Eléonore Beurel, Charles B. Nemeroff, Beurel, Eléonore, Nemeroff, Charles B. |
Abstract |
Stress mediates the activation of a variety of systems ranging from inflammatory to behavioral responses. In this review we focus on two neuropeptide systems, corticotropin-releasing factor (CRF) and arginine vasopressin (AVP), and their roles in regulating stress responses. Both peptides have been demonstrated to be involved in anxiogenic and depressive effects, actions mediated in part through their regulation of the hypothalamic-pituitary-adrenal axis and the release of adrenocorticotropic hormone. Because of the depressive effects of CRF and AVP, drugs modifying the stress-associated detrimental actions of CRF and AVP are under development, particularly drugs antagonizing CRF and AVP receptors for therapy in depression. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Germany | 1 | 25% |
United States | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 75% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 67 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 13 | 19% |
Student > Ph. D. Student | 12 | 18% |
Researcher | 7 | 10% |
Other | 5 | 7% |
Student > Master | 5 | 7% |
Other | 14 | 21% |
Unknown | 11 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Neuroscience | 16 | 24% |
Psychology | 9 | 13% |
Medicine and Dentistry | 8 | 12% |
Biochemistry, Genetics and Molecular Biology | 6 | 9% |
Agricultural and Biological Sciences | 4 | 6% |
Other | 7 | 10% |
Unknown | 17 | 25% |