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Antibiotic Discovery and Development

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Cover of 'Antibiotic Discovery and Development'

Table of Contents

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    Book Overview
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    Chapter 1 The Early History of Antibiotic Discovery: Empiricism Ruled
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    Chapter 2 Rational Approaches to Antibacterial Discovery: Pre-Genomic Directed and Phenotypic Screening
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    Chapter 3 Beta-Lactam Antibiotics
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    Chapter 4 Review of the Quinolone Family
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    Chapter 5 Tetracyclines
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    Chapter 6 Macrolides and Ketolides
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    Chapter 7 Aminoglycosides
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    Chapter 8 Oxazolidinone Antibacterial Agents
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    Chapter 9 Glycopeptides and Lipoglycopeptides
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    Chapter 10 Efflux-Mediated Antimicrobial Resistance
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    Chapter 11 Structural Mechanisms of β-Lactam Antibiotic Resistance in Penicillin-Binding Proteins
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    Chapter 12 Evolution of β-Lactamases: Past, Present, and Future
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    Chapter 13 Inducible Resistance to Macrolide Antibiotics
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    Chapter 14 Fluoroquinolone Resistance: Mechanisms, Restrictive Dosing, and Anti-Mutant Screening Strategies for New Compounds
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    Chapter 15 Glycopeptide Resistance
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    Chapter 16 Acquired Tetracycline Resistance Genes
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    Chapter 17 Evolution of Molecular Techniques for the Characterization of MRSA Clones
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    Chapter 18 Mechanisms of Penicillin Resistance in Streptococcus pneumoniae : Targets, Gene Transfer and Mutations
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    Chapter 19 Clinical Aspects of Multi-Drug Resistant Enterococci
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    Chapter 20 Clinical Issues of Resistance: Problematic Microbes: Enterobacteriaceae
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    Chapter 21 Pseudomonas aeruginosa : A Persistent Pathogen in Cystic Fibrosis and Hospital-Associated Infections
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    Chapter 22 Drug Resistant and Persistent Tuberculosis: Mechanisms and Drug Development
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    Chapter 23 Resistance Trends and Susceptibility Profiles in the US Among Prevalent Clinical Pathogens: Lessons from Surveillance
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    Chapter 24 Chemical Properties of Antimicrobials and Their Uniqueness
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    Chapter 25 Natural Products in the 21st Century
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    Chapter 26 Permeability of Bacteria to Antibacterial Agents
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    Chapter 27 Novel Antibacterial Targets/Identification of New Targets by Comparative Genomics
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    Chapter 28 Cell-Based Screening in Antibacterial Discovery
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    Chapter 29 Enzyme-Based Screens in HTS
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    Chapter 30 Antibacterial Inhibitors of the Essential Cell Division Protein FtsZ
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    Chapter 31 Structure-Guided Discovery of New Antimicrobial Agents
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    Chapter 32 NMR in Infection Research
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    Chapter 33 A Review of Animal Models Used for Antibiotic Evaluation
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    Chapter 34 In Vivo Pharmacodynamic Modeling for Drug Discovery
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    Chapter 35 Applications of Pharmacokinetic/Pharmacodynamic Models for the Development of Antimicrobial Agents
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    Chapter 36 Antibiotic Drug Development: Moving Forward into the Clinic
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    Chapter 37 Stimulating Antibacterial Research and Development: Sense and Sensibility?
Attention for Chapter 3: Beta-Lactam Antibiotics
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Chapter title
Beta-Lactam Antibiotics
Chapter number 3
Book title
Antibiotic Discovery and Development
Published by
Springer, Boston, MA, January 2012
DOI 10.1007/978-1-4614-1400-1_3
Book ISBNs
978-1-4614-1399-8, 978-1-4614-1400-1
Authors

Malcolm G. P. Page

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 374 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 374 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 104 28%
Student > Master 36 10%
Student > Ph. D. Student 30 8%
Student > Doctoral Student 16 4%
Researcher 15 4%
Other 19 5%
Unknown 154 41%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 58 16%
Agricultural and Biological Sciences 28 7%
Medicine and Dentistry 27 7%
Chemistry 24 6%
Pharmacology, Toxicology and Pharmaceutical Science 24 6%
Other 52 14%
Unknown 161 43%