Report for: Orphan G Protein-Coupled Receptors and Novel Neuropeptides

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Chapter title	The NPB/NPW neuropeptide system and its role in regulating energy homeostasis, pain, and emotion.
Chapter number	56
Book title	Orphan G Protein-Coupled Receptors and Novel Neuropeptides
Published in	Results and problems in cell differentiation, January 2008
DOI	10.1007/400_2007_056
Pubmed ID	18204824
Book ISBNs	978-3-54-078350-3, 978-3-54-078351-0
Authors	Mari Hondo, Makoto Ishii, Takeshi Sakurai, Hondo, Mari, Ishii, Makoto, Sakurai, Takeshi
Abstract	Neuropeptide B (NPB) and neuropeptide W (NPW) are neuropeptides that were recently identified as endogenous ligands for the previously orphan G-protein coupled receptors, GPR7 (NPBWR1) and GPR8 (NPBWR2). This neuropeptide system is thought to have a role in regulating feeding behavior, energy homeostasis, neuroendocrine function, and modulating inflammatory pain. Strong and discrete expression of their receptors in the extended amygdala suggests a potential role in regulating stress responses, emotion, anxiety and fear; however, there have been no functional studies to date to support this possibility. Future studies of NPB/NPW using both pharmacological and phenotypic analysis of genetically engineered mice will lead to further elucidation of the physiological role of this novel neuropeptide system.

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Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country	Count	As %
Mexico	1	3%
Canada	1	3%
Unknown	30	94%

Demographic breakdown

Readers by professional status	Count	As %
Researcher	8	25%
Student > Ph. D. Student	4	13%
Student > Master	4	13%
Student > Doctoral Student	3	9%
Professor	3	9%
Other	5	16%
Unknown	5	16%

Readers by discipline	Count	As %
Agricultural and Biological Sciences	10	31%
Neuroscience	7	22%
Biochemistry, Genetics and Molecular Biology	4	13%
Medicine and Dentistry	2	6%
Nursing and Health Professions	1	3%
Other	2	6%
Unknown	6	19%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2014.

All research outputs

#7,455,523

of 22,792,160 outputs

Outputs from Results and problems in cell differentiation

#28

of 217 outputs

Outputs of similar age

#41,756

of 156,222 outputs

Outputs of similar age from Results and problems in cell differentiation

of 8 outputs

Altmetric has tracked 22,792,160 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.

So far Altmetric has tracked 217 research outputs from this source. They receive a mean Attention Score of 2.1. This one has done well, scoring higher than 76% of its peers.

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We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them

Orphan G Protein-Coupled Receptors and Novel Neuropeptides

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Attention Score in Context