Chapter title |
Engineering of M13 Bacteriophage for Development of Tissue Engineering Materials
|
---|---|
Chapter number | 32 |
Book title |
Virus-Derived Nanoparticles for Advanced Technologies
|
Published in |
Methods in molecular biology, January 2018
|
DOI | 10.1007/978-1-4939-7808-3_32 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7806-9, 978-1-4939-7808-3
|
Authors |
Hyo-Eon Jin, Seung-Wuk Lee, Jin, Hyo-Eon, Lee, Seung-Wuk |
Abstract |
M13 bacteriophages have several qualities that make them attractive candidates as building blocks for tissue regenerating scaffold materials. Through genetic engineering, a high density of functional peptides and proteins can be simultaneously displayed on the M13 bacteriophage's outer coat proteins. The resulting phage can self-assemble into nanofibrous network structures and can guide the tissue morphogenesis through proliferation, differentiation and apoptosis. In this manuscript, we will describe methods to develop major coat-engineered M13 phages as a basic building block and aligned tissue-like matrices to develop regenerative nanomaterials. |
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Demographic breakdown
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
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Unknown | 16 | 100% |
Demographic breakdown
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Student > Bachelor | 3 | 19% |
Student > Master | 2 | 13% |
Student > Ph. D. Student | 2 | 13% |
Researcher | 2 | 13% |
Student > Doctoral Student | 1 | 6% |
Other | 1 | 6% |
Unknown | 5 | 31% |
Readers by discipline | Count | As % |
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Materials Science | 2 | 13% |
Immunology and Microbiology | 1 | 6% |
Engineering | 1 | 6% |
Unknown | 5 | 31% |