Precise values for #cholesterol activity measurements will allow a more quantitative treatment of the experimental data, which so far have been qualitatively described using terms like "cholesterol accessibility". 2/8 https://t.co/Wi5f1D0su3
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Membrane Attack Complex/Perforin (MACPF) and cholesterol-dependent cytolysins (CDCs) form the MACPF/CDC superfamily of important effector proteins widespread in nature. MACPFs and CDCs were discovered... https://t.co/SIvgWBSkzK
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Five different cholesterol-dependent cytolysins (CDCs) have now had their atomic structures solved. Here their structures are compared... https://t.co/RA9LUngL5n
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Cholesterol-dependent cytolysins (CDCs) constitute a family of pore-forming toxins secreted by Gram-positive bacteria. These toxins form transmembrane pores by inserting a large beta-barrel into cholesterol-containing membrane bilayers. Binding of water...