| Chapter title |
Mass Spectrometry in Clinical Laboratory: Applications in Therapeutic Drug Monitoring and Toxicology.
|
|---|---|
| Chapter number | 1 |
| Book title |
Clinical Applications of Mass Spectrometry in Drug Analysis
|
| Published in |
Methods in molecular biology, January 2016
|
| DOI | 10.1007/978-1-4939-3252-8_1 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-3251-1, 978-1-4939-3252-8
|
| Authors |
Garg, Uttam, Zhang, Yan Victoria, Uttam Garg, Yan Victoria Zhang |
| Abstract |
Mass spectrometry (MS) has been used in research and specialized clinical laboratories for decades as a very powerful technology to identify and quantify compounds. In recent years, application of MS in routine clinical laboratories has increased significantly. This is mainly due to the ability of MS to provide very specific identification, high sensitivity, and simultaneous analysis of multiple analytes (>100). The coupling of tandem mass spectrometry with gas chromatography (GC) or liquid chromatography (LC) has enabled the rapid expansion of this technology. While applications of MS are used in many clinical areas, therapeutic drug monitoring, drugs of abuse, and clinical toxicology are still the primary focuses of the field. It is not uncommon to see mass spectrometry being used in routine clinical practices for those applications. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 50% |
| Canada | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 26 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 6 | 23% |
| Student > Bachelor | 5 | 19% |
| Student > Master | 3 | 12% |
| Other | 1 | 4% |
| Professor | 1 | 4% |
| Other | 1 | 4% |
| Unknown | 9 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 3 | 12% |
| Biochemistry, Genetics and Molecular Biology | 3 | 12% |
| Chemistry | 3 | 12% |
| Medicine and Dentistry | 3 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 8% |
| Other | 4 | 15% |
| Unknown | 8 | 31% |