| Chapter title |
Comprehensive Urine Drug Screen by Gas Chromatography/Mass Spectrometry (GC/MS)
|
|---|---|
| Chapter number | 15 |
| Book title |
Clinical Applications of Mass Spectrometry in Drug Analysis
|
| Published in |
Methods in molecular biology, January 2016
|
| DOI | 10.1007/978-1-4939-3252-8_15 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-3251-1, 978-1-4939-3252-8
|
| Authors |
Bheemraj Ramoo, Melissa Funke, Clint Frazee, Uttam Garg |
| Abstract |
Drug screening is an essential component of clinical toxicology laboratory service. Some laboratories use only automated chemistry analyzers for limited screening of drugs of abuse and few other drugs. Other laboratories use a combination of various techniques such as immunoassays, colorimetric tests, and mass spectrometry to provide more detailed comprehensive drug screening. Mass spectrometry, gas or liquid, can screen for hundreds of drugs and is often considered the gold standard for comprehensive drug screening. We describe an efficient and rapid gas chromatography/mass spectrometry (GC/MS) method for comprehensive drug screening in urine which utilizes a liquid-liquid extraction, sample concentration, and analysis by GC/MS. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 31 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 8 | 26% |
| Student > Ph. D. Student | 4 | 13% |
| Other | 3 | 10% |
| Student > Master | 3 | 10% |
| Student > Doctoral Student | 2 | 6% |
| Other | 3 | 10% |
| Unknown | 8 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 8 | 26% |
| Engineering | 2 | 6% |
| Biochemistry, Genetics and Molecular Biology | 2 | 6% |
| Nursing and Health Professions | 1 | 3% |
| Agricultural and Biological Sciences | 1 | 3% |
| Other | 5 | 16% |
| Unknown | 12 | 39% |