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Meningococcal Vaccines

Overview of attention for book
Attention for Chapter: Purification of Capsular Polysaccharide
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (72nd percentile)

Mentioned by

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1 Wikipedia page

Citations

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18 Dimensions

Readers on

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8 Mendeley
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Chapter title
Purification of Capsular Polysaccharide
Book title
Meningococcal Vaccines
Published in
Methods in molecular medicine, June 2001
DOI 10.1385/1-59259-148-5:41
Pubmed ID
Book ISBNs
978-1-59259-148-0, 978-0-89603-801-1
Authors

Yang, Qingling, Jennings, Harold, Qingling Yang, Harold Jennings

Abstract

Meningococcus is an aerobic, fastidious, Gram-negative diplococcus that is found only in humans. Its cell wall has a cytoplasmic membrane, a peptidoglycan layer, and an outer membrane. Meningococci isolated from the bloodstream or the spinal fluid are almost always encapsulated. The capsules are polysaccharides, which consist of repeating sugar units (1,2). The capsular polysaccharide can be isolated, purified, and chemically and physically defined. Based on the chemical and immunological specificity of its capsular polysaccharides, Neisseria meningitidis has been classified serologically into groups A, B, C, 29E, H, I, K, L, W135, X, Y and Z (2). Of these, groups A, B, and C are responsible for approx 90% of meningococcal meningitis, and group B meningococcus is responsible for the majority of meningococcal disease in industrialized countries (1,2). The structures of the repeating units of the meningococcal polysaccharides have been elucidated and are shown in Table 1. Table 1 Structures of the Capsular Polysaccharides of N. meningitidis Group Structure of repeating unit Reference A →6)α-D-ManNAc(1-PO4→ (8) 3 ↑ OAc B →8)α-D-NeuNAc(2→ (5) C →9)α-D-NeuNAc(2→ (5) 7/8 ↑ OAc H →4)α-D-Gal (l→2) glycerol 3-PO(4)→ (6) L →3)α-D-GlcNAc (l→3) β-D-GlcNAc (l→3) α-D-GlcNAc-1-PO(4)→ (7) X →4)α-D-GlcNAc-1 -PO(4)→ (4) Y →6)α-D-Glc (l→4) α-D-NeuNAc (2→ (OAc) (9) W135 →6)α-D-Gal (l→4) α-D-NeuNAc (2→ (9) Z →3)α-D-GalNAc (1→1) glycerol 3-PO(4)→ (10) 29E →7)β-D-KDO (l→3) α-D-GalNAc (l→ (11).

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 13%
Unknown 7 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 2 25%
Student > Bachelor 1 13%
Other 1 13%
Student > Master 1 13%
Unknown 3 38%
Readers by discipline Count As %
Medicine and Dentistry 2 25%
Biochemistry, Genetics and Molecular Biology 1 13%
Chemistry 1 13%
Immunology and Microbiology 1 13%
Unknown 3 38%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2012.
All research outputs
#816,763
of 3,628,758 outputs
Outputs from Methods in molecular medicine
#3
of 27 outputs
Outputs of similar age
#24,774
of 95,279 outputs
Outputs of similar age from Methods in molecular medicine
#1
of 1 outputs
Altmetric has tracked 3,628,758 research outputs across all sources so far. This one has received more attention than most of these and is in the 63rd percentile.
So far Altmetric has tracked 27 research outputs from this source. They receive a mean Attention Score of 1.9. This one scored the same or higher as 24 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,279 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them