Chapter title |
Toll receptors in Drosophila: a family of molecules regulating development and immunity.
|
---|---|
Chapter number | 4 |
Book title |
Toll-Like Receptor Family Members and Their Ligands
|
Published in |
Current topics in microbiology and immunology, January 2002
|
DOI | 10.1007/978-3-642-59430-4_4 |
Pubmed ID | |
Book ISBNs |
978-3-64-263975-3, 978-3-64-259430-4
|
Authors |
Imler, J L, Hoffmann, J A, Imler, J. L., Hoffmann, J. A., J. L. Imler, J. A. Hoffmann |
Abstract |
In recent years, Toll-like receptors (TLRs) have emerged as key receptors which detect microbes and initiate an inflammatory response. The Toll receptor was originally identified and characterized 14 years ago for its role in the embryonic development of the fruit-fly Drosophila melanogaster. Subsequently, it was also shown to be an essential component of the signaling pathway mediating the anti-fungal host defense in this model organism. New factors involved in the activation of the Toll receptor or in intracytoplasmic signaling during the immune response in Drosophila have recently been identified. The existence of significant functional differences between mammalian TLRs and Drosophila Toll receptors is also becoming apparent. |
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Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 3 | 7% |
United Kingdom | 2 | 4% |
Germany | 1 | 2% |
Egypt | 1 | 2% |
Unknown | 38 | 84% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 13 | 29% |
Student > Ph. D. Student | 7 | 16% |
Professor > Associate Professor | 6 | 13% |
Professor | 5 | 11% |
Student > Master | 3 | 7% |
Other | 5 | 11% |
Unknown | 6 | 13% |
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Biochemistry, Genetics and Molecular Biology | 9 | 20% |
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Environmental Science | 2 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
Other | 6 | 13% |
Unknown | 7 | 16% |