Toll-Like Receptor Family Members and Their Ligands
Springer Berlin Heidelberg
Chapter title |
Bacterial CpG-DNA Licenses TLR9
|
---|---|
Chapter number | 9 |
Book title |
Toll-Like Receptor Family Members and Their Ligands
|
Published in |
Current topics in microbiology and immunology, February 2016
|
DOI | 10.1007/978-3-642-59430-4_9 |
Pubmed ID | |
Book ISBNs |
978-3-64-263975-3, 978-3-64-259430-4
|
Authors |
S. Bauer, H. Wagner, Bauer, S., Wagner, H. |
Abstract |
The family of Toll-like receptors (TLRs) plays an important role in the innate immune response to pathogens. TLRs sense pathogen associated molecular patterns (PAMP) and lead to the stimulation of immune cells. In man, so far ten members (TLR1-10) have been reported. This review focuses on TLR9 which is an essential component for the recognition of bacterial CpG-DNA. Expression of TLR9 and structural consideration as well as direct ligand interaction of TLR9 and CpG-DNA are discussed. |
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Student > Doctoral Student | 2 | 8% |
Other | 6 | 23% |
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Other | 0 | 0% |
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