Table of Contents

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   Book Overview
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   Chapter 1 1 H-MR Spectroscopic Monitoring of Posttraumatic Metabolism Following Controlled Cortical Impact Injury: Pilot Study
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   Chapter 2 Heterogeneous Mechanisms of Early Edema Formation in Cerebral Contusion: Diffusion MRI and ADC Mapping Study
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   Chapter 3 Metabolic Changes in Pericontusional Oedematous Areas in Mild Head Injury Evaluated by 1 H MRS
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   Chapter 4 Malignancy of Brain Tumors Evaluated by Proton Magnetic Resonance Spectroscopy ( 1 H-MRS) in Vitro
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   Chapter 5 rCBF in Hemorrhagic, Non-Hemorrhagic and Mixed Contusions After Severe Head Injury and its Effect on Perilesional Cerebral Blood Flow
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   Chapter 6 Glutathione Homeostasis and Leukotriene-Induced Permeability in Human Blood-Brain Barrier Endothelial Cells Subjected to in Vitro Ischemia
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   Chapter 7 Comparison of NAA Measures by MRS and HPLC
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   Chapter 8 Influence of the Bradykinin Bl/B2-Receptor-Antagonist B 9430 on the Cerebral Microcirculation and Outcome of Gerbils from Global Cerebral Ischemia
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    Chapter 9 Evolution of Energy Failure after Repeated Cerebral Ischemia in Gerbils
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    Chapter 10 Indomethacin and Cyclosporin a Inhibit in Vitro Ischemia-Induced Expression of ICAM-1 and Chemokines in Human Brain Endothelial Cells
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    Chapter 11 The Selectin Superfamily: The Role of Selectin Adhesion Molecules in Delayed Cerebral Ischaemia After Aneurysmal Subarachnoid Haemorrhage
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    Chapter 12 Traumatic Brain Injury in Mice Deficient in Poly-ADP(Ribose) Polymerase: A Preliminary Report
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    Chapter 13 Increased Immunolocalization of Nitric Oxide Synthases During Blood-Brain Barrier Breakdown and Cerebral Edema
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    Chapter 14 Biological Functions of Extravasated Serum IgG in Rat Brain
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    Chapter 15 Possible Reverse Transport of β-Amyloid Peptide Across the Blood-Brain Barrier
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    Chapter 16 Reducing Conditions Produce a Loss of Neuroprotective Efficacy of Competitive but not non-Competitive Antagonists in a Model of NMDA-Mediated Excitotoxicity in Organotypic Hippocampal Slice Cultures
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    Chapter 17 Role of Nitric Oxide in Blood-Brain Barrier Permeability, Brain Edema and Cell Damage Following Hyperthermic Brain Injury. An Experimental Study Using EGB-761 and Gingkolide B Pretreatment in the Rat
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    Chapter 18 Extracts of Ginkgo Biloba and Panax Ginseng Protect Brain Proteins from Free Radical Induced Oxidative Damage in Vitro
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    Chapter 19 p-Chlorophenylalanine, an Inhibitor of Serotonin Synthesis Reduces Blood-Brain Barrier Permeability, Cerebral Blood Flow, Edema Formation and Cell Injury Following Trauma to the Rat Brain
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    Chapter 20 S-100 Serum Levels and Outcome After Severe Head Injury
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    Chapter 21 A Microstructural Study of Spinal Cord Edema
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    Chapter 22 Vasogenic Oedema and Brain Infarction in an Experimental Penumbra Model
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    Chapter 23 Effects of Chronic Deep Hypoxia on the Expression of Nitric Oxide Synthase in the Rat Brain
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    Chapter 24 Adrenergic Mediation of TNFα-Stimulated ICAM-1 Expression on Human Brain Microvascular Endothelial Cells
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    Chapter 25 Time Course of Apoptotic Cell Death After Experimental Neurotrauma
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    Chapter 26 The Permissive Nature of Blood Brain Barrier (BBB) Opening in Edema Formation Following Traumatic Brain Injury
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    Chapter 27 Endothelin-1 and Nitric Oxide Affect Human Cerebromicrovascular Endothelial Responses and Signal Transduction
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    Chapter 28 LF16-0687 A Novel Non-Peptide Bradykinin B2 Receptor Antagonist Reduces Vasogenic Brain Edema from a Focal Lesion in Rats
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    Chapter 29 AT1 Receptor Antagonist Prevents Brain Edema Without Lowering Blood Pressure
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    Chapter 30 The Effects of Dopamine on Edema Formation in two Models of Traumatic Brain Injury
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    Chapter 31 A New Antioxidant Compound H-290/51 Attenuates Upregulation of Constitutive Isoform of Heme Oxygenase (HO-2) Following Trauma to the Rat Spinal Cord
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    Chapter 32 A Bradykinin BK 2 Receptor Antagonist HOE-140 Attenuates Blood-Spinal Cord Barrier Permeability Following a Focal Trauma to the Rat Spinal Cord
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    Chapter 33 Combined Therapy Utilizing a Novel Na + /H + Exchange Inhibitor (SM-20220) and THAM for Ischemic Brain Edema
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    Chapter 34 Bradykinin 2 Receptor Antagonist LF 16-0687Ms Reduces Posttraumatic Brain Edema
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    Chapter 35 Influence of Alcohol Exposure on S-100b Serum Levels
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    Chapter 36 Laser Doppler Scanning: How Many Measurements are Required to Assess Regional Cerebral Blood Flow?
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    Chapter 37 Assessment of 2-Chloroadenosine Treatment After Experimental Traumatic Brain Injury in the Rat Using Arterial Spin-Labeled MRI: A Preliminary Report
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    Chapter 38 Time Course of Trace of Diffusion Tensor [Trace(D)] and Histology in Brain Edema
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    Chapter 39 L-Histidine but not D-Histidine Attenuates Brain Edema Following Cryogenic Injury in Rats
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    Chapter 40 Oxygen Delivery and Oxygen Tension in Cerebral Tissue During Global Cerebral Ischaemia: A Swine Model
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    Chapter 41 ICP and MABP Following Traumatic Subarachnoid Hemorrhage in the Rat
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    Chapter 42 Real Time Monitoring of Glutamate Following Fluid Percussion Brain Injury with Hypoxia in the Rat
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    Chapter 43 The Synergistic Effect of Acute Subdural Hematoma Combined with Diffuse Traumatic Brain Injury on Brain Edema
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    Chapter 44 Mitogen-Activated Protein Kinase Plays an Important Role in Hemolysate-Induced Contraction in Rabbit Basilar Artery
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    Chapter 45 Morphological Presentation of Posttraumatic Vasospasm
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    Chapter 46 Role of Tyrosine Kinase in Fibroblast Compaction and Cerebral Vasospasm
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    Chapter 47 Toxin-Induced Vasogenic Cerebral Oedema in a Rat Model
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    Chapter 48 Expression of Water Channel mRNA Following Cerebral Ischemia
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    Chapter 49 Brain Oxygen Tension During Hyperoxia in a Swine Model of Cerebral Ischaemia
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    Chapter 50 The Synergistic Effect of High K + and Hypoxia on Extracellular Concentrations of Neuroactive Amino Acid in Hippocampus
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    Chapter 51 Spreading Depression Induces Permanent Cell Swelling Under Penumbra Conditions
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    Chapter 52 Cerebral Blood Flow and the Secondary Growth of Brain Tissue Necrosis After Trauma
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    Chapter 53 The Role of Proteolytic Enzymes in Focal Ischaemic Brain Damage
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    Chapter 54 Effect of Intracerebral Lesions Detected in Early MRI on Outcome After Acute Brain Injury
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    Chapter 55 Effects of Brain Oedema in the Measurement of Ischaemic Brain Damage in Focal Cerebral Infarction
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    Chapter 56 Characterizing Edema Associated with Cortical Contusion and Secondary Insult Using Magnetic Resonance Spectroscopy
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    Chapter 57 Plasminogen Activator Inhibitor-1 in Patients with Ischemic Stroke
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    Chapter 58 Experimental Study on Brain Oxygenation in Relation to Tissue Water Redistribution and Brain Oedema
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    Chapter 59 Mn-SOD and Bcl-2 Expression After Repeated Hyperbaric Oxygenation
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    Chapter 60 Neurotrophic Factors Attenuate Alterations in Spinal Cord Evoked Potentials and Edema Formation Following Trauma to the Rat Spinal Cord
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    Chapter 61 Spinal Cord Injury Induced c-fos Expression is Reduced by p-CPA, a Serotonin Synthesis Inhibitor. An Experimental Study Using Immunohistochemistry in the Rat
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    Chapter 62 Lipocortin-1 Fails to Ameliorate Ischemic Brain Edema in the Cat
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    Chapter 63 Lipocortin-1 Fails to Ameliorate Cold-Injury Brain Edema in the Rat
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    Chapter 64 Hepatocyte Growth Factor Reduces Infarct Volume After Transient Focal Cerebral Ischemia in Rats
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    Chapter 65 Clinical Use of Lidocaine for Control of Stroke Oedema in the Posterior Cranial Fossa Accompanied by Acute Hydrocephalus
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    Chapter 66 Usefulness of Niravoline, an Arginine Vasopressin Inhibitor, on Tumour-Origin Brain Oedema
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    Chapter 67 Broad-Spectrum Cation Channel Inhibition by LOE 908 MS Reduces Infarct Volume in Vivo and Postmortem in Focal Cerebral Ischemia in the Rat
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    Chapter 68 A Glycine Site Antagonist ZD9379 Reduces Number of Spreading Depressions and Infarct Size in Rats with Permanent Middle Cerebral Artery Occlusion
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    Chapter 69 Effects of Inducible Nitric Oxide Synthase Inhibition on Cerebral Edema in Severe Hypertension
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    Chapter 70 Sphingolipid Biosynthesis by L-PDMP After Rat MCA Occlusion
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    Chapter 71 Protective Effect of a Novel Vitamin E Derivative on Experimental Traumatic Brain Edema in Rats — Preliminary Study
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    Chapter 72 Distinguishing Between Cellular and Vasogenic Edema in Head Injured Patients with Focal Lesions Using Magnetic Resonance Imaging
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    Chapter 73 Interstitial Lactate in the Peritraumatic Penumbra of Rat Brain
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    Chapter 74 Attenuation of Secondary Lesion Growth in the Brain After Trauma by Selective Inhibition of the Inducible No-Synthase
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    Chapter 75 Evidence for Lactate Uptake After Rat Fluid Percussion Brain Injury
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    Chapter 76 Topical Application of Brain Derived Neurotrophic Factor Influences Upregulation of Constitutive Isoform of Heme Oxygenase in the Spinal Cord Following Trauma An Experimental Study Using Immunohistochemistry in the Rat
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    Chapter 77 Time Profile of Neuron Specific Enolase Serum Levels After Experimental Brain Injury in Rat
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    Chapter 78 Isoflurane Doubles Plasma Glutamate and Increases Posttraumatic Brain Edema
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    Chapter 79 Mechanical injury alters volume activated ion channels in cortical astrocytes.
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    Chapter 80 Thyroid Hormones in Comatose Patients with Traumatic Brain Injury
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    Chapter 81 S-100b as a Screening Marker of the Severity of Minor Head Trauma (MHT) — a Pilot Study
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    Chapter 82 Influences of Secondary Injury Following Traumatic Brain Injury in Developing Versus Adult Rats
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    Chapter 83 The Role of Decompressive Craniectomy in the Treatment of Uncontrollable Post-Traumatic Intracranial Hypertension
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    Chapter 84 The Impact of Acute Hyponatraemia on Severe Traumatic Brain Injury in Rats
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    Chapter 85 Validation of a Closed Head Injury Model for use in Long-Term Studies
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    Chapter 86 Diffuse Axonal Injury with or Without an Evacuated Intracranial Hematoma in Head Injured Patients. Are They Different Lesions?
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    Chapter 87 Increased Adrenomedullin in Cerebrospinal Fluid After Traumatic Brain Injury in Children: A Preliminary Report
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    Chapter 88 Low Extracellular (ECF) Glucose Affects the Neurochemical Profile in Severe Head-Injured Patients
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    Chapter 89 On-line monitoring of substrate delivery and brain metabolism in head injury.
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    Chapter 90 Extracellular Glutamate and Aspartate in Head Injured Patients
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    Chapter 91 Substrate Delivery and Ionic Balance Disturbance After Severe Human Head Injury
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    Chapter 92 Assessment of the Variation in Cerebrovascular Reactivity in Head Injured Patients
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    Chapter 93 Non-Invasive Cerebral Perfusion Pressure (nCPP): Evaluation of the Monitoring Methodology in Head Injured Patients
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    Chapter 94 A Study of the Effects of Using Different Cerebral Perfusion Pressure (CPP) Thresholds to Quantify CPP “Secondary Insults” in Children
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    Chapter 95 Does an Increase in Cerebral Perfusion Pressure Always Mean a Better Oxygenated Brain? A Study in Head-Injured Patients
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    Chapter 96 Continuous Monitoring of ICP and CPP Following ICH and its Relationship to Clinical, Radiological and Surgical Parameters
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    Chapter 97 Neuromuscular Blocking Agents in Neurointensive Care
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    Chapter 98 The Role of Nitric Oxide in Reoxygenation Injury of Brain Microvascular Endothelial Cells
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     Chapter 99 The Use of Decompressive Craniectomy for the Management of Severe Head Injuries
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     Chapter 100 Transcranial Doppler Ultrasonography (TCD) in Ventilated Head Injured Patients: Correlation with Stable Xenon-Enhanced CT
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     Chapter 101 Continuous Assessment of Cerebral Autoregulation — Clinical Verification of the Method in Head Injured Patients
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     Chapter 102 False Autoregulation (Pseudoautoregulation) in Patients with Severe Head Injury. Its Importance in CPP Management
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     Chapter 103 Multi-Centre Assessment of the Spiegelberg Compliance Monitor: Preliminary Results
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     Chapter 104 Intracranial Hypertension Influences the Resolution of Vasogenic Brain Edema Following Intracerebral Hemorrhage
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     Chapter 105 Induction of colligin may attenuate brain edema following intracerebral hemorrhage.
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     Chapter 106 Oxyhemoglobin Produces Necrosis in Cultured Smooth Muscle Cells
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     Chapter 107 Thrombin preconditioning, heat shock proteins and thrombin-induced brain edema.
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     Chapter 108 Changes in Cerebral Blood Flow as Measured by HMPAO SPECT in Patients Following Spontaneous Intracerebral Haemorrhage
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     Chapter 109 Surgical Trial in Intracerebral Haemorrhage (S.T.I.C.H)
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     Chapter 110 Postischemic Hypothermia Attenuates Apoptotic Cell Death in Transient Focal Ischemia in Rats
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     Chapter 111 Effects of Hypothermia on Intracranial Hemodynamics and Ischemic Brain Damage-Studies in the Rat Acute Subdural Hematoma Model
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     Chapter 112 Blockade of Histamine H 2 Receptors Attenuate Blood-Brain Barrier Permeability, Cerebral Blood Flow Disturbances, Edema Formation and Cell Reactions Following Hyperthermic Brain Injury in the Rat
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     Chapter 113 Selective Alteration of Calcitonin Gene Related Peptide in Hyperthermic Brain Injury. An Experimental Study in the Rat Brain Using Immunohistochemistry
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     Chapter 114 Protective Effect of Mild Hypothermia on Symptomatic Vasospasm: A Preliminary Report
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     Chapter 115 Influence of Hypothermia on Cell Volume and Cytotoxic Swelling of Glial Cells in Vitro
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     Chapter 116 Clinical Experiences with the Dual-Switch Valve in Patients with Normal Pressure Hydrocephalus
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     Chapter 117 Endoscopic Ventriculostomy Versus Shunt Operation in Normal Pressure Hydrocephalus: Diagnostics and Indication