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Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development

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Cover of 'Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development'

Table of Contents

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    Book Overview
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    Chapter 1 Methods for Quantifying Insulin Sensitivity and Determining Insulin Time-Action Profiles
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    Chapter 2 Assessment of β-Cell Function
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    Chapter 3 Isotopic Tracers for the Measurement of Metabolic Flux Rates
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    Chapter 4 Imaging Techniques for the Assessment of Ectopic Fat in Liver and Skeletal Muscle
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    Chapter 5 Positron-Emission Tomography and Computed Tomography Measurement of Brown Fat Thermal Activation: Key Tools for Developing Novel Pharmacotherapeutics for Obesity and Diabetes
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    Chapter 6 Assessment of Body Composition
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    Chapter 7 Measurement of Energy Expenditure
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    Chapter 8 Omics: Potential Role in Early-Phase Drug Development
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    Chapter 9 Early Phase Metabolic Research with Reference to Special Populations
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    Chapter 10 Quantitative Approaches in Translational Research: An Overview
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    Chapter 11 Computational Modelling of Energy Metabolism and Body Composition Dynamics
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    Chapter 12 Regulatory Considerations for Early Clinical Development of Drugs for Diabetes, Obesity, and Cardiometabolic Disorders
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