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Stress-Inducible Cellular Responses

Overview of attention for book
Cover of 'Stress-Inducible Cellular Responses'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Introduction
  3. Altmetric Badge
    Chapter 2 Normal protein folding machinery
  4. Altmetric Badge
    Chapter 3 Roles for hsp70 in protein translocation across membranes of organelles
  5. Altmetric Badge
    Chapter 4 Protein folding and assembly in the endoplasmic reticulum
  6. Altmetric Badge
    Chapter 5 Involvement of molecular chaperones in intracellular protein breakdown
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    Chapter 6 Molecular chaperoning of steroid hormone receptors.
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    Chapter 7 Protein disulfide isomerase: a multifunctional protein of the endoplasmic reticulum.
  9. Altmetric Badge
    Chapter 8 Introduction
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    Chapter 9 Sensing stress and responding to stress.
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    Chapter 10 The transcriptional regulation of heat shock genes: a plethora of heat shock factors and regulatory conditions.
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    Chapter 11 Transcriptional regulation of stress-inducible genes in procaryotes
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    Chapter 12 The impact of oxidative stress on eukaryotic iron metabolism
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    Chapter 13 Heat-shock induced protein modifications and modulation of enzyme activities
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    Chapter 14 SOS response as an adaptive response to DNA damage in prokaryotes.
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    Chapter 15 Introduction
  17. Altmetric Badge
    Chapter 16 Transcriptional regulators of oxidative stress-inducible genes in prokaryotes and eukaryotes
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    Chapter 17 UV activation of mammalian stress protiens
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    Chapter 18 Signaling events controlling the molecular response to genotoxic stress
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    Chapter 19 Mammalian DNA repair responses and genomic instability
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    Chapter 20 Toxic metal-responsive gene transcription.
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    Chapter 21 Tumor necrosis factor and lymphotoxin: Protection against oxidative stress through induction of MnSOD
  23. Altmetric Badge
    Chapter 22 Introduction
  24. Altmetric Badge
    Chapter 23 Viral infection
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    Chapter 24 Infection, autoimmunity and autoimmune disease
  26. Altmetric Badge
    Chapter 25 Stress proteins in inflammation
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    Chapter 26 Attenuated heat shock transcriptional response in aging: molecular mechanism and implication in the biology of aging.
  28. Altmetric Badge
    Chapter 27 Applications of stress responses in toxicology and pharmacology
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    Chapter 28 Stress proteins as molecular biomarkers for environmental toxicology
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    Chapter 29 Thermotolerance and heat shock proteins: possible involvement of Ku autoantigen in regulating Hsp70 expression.
  31. Altmetric Badge
    Chapter 30 Heat shock proteins as immunological carriers and vaccines
  32. Altmetric Badge
    Chapter 31 Regulation of thermotolerance and ischemic tolerance
  33. Altmetric Badge
    Chapter 32 Future applications
  34. Altmetric Badge
    Chapter 33 Outlook
Attention for Chapter 9: Sensing stress and responding to stress.
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Chapter title
Sensing stress and responding to stress.
Chapter number 9
Book title
Stress-Inducible Cellular Responses
Published in
EXS, January 1996
DOI 10.1007/978-3-0348-9088-5_9
Pubmed ID
Book ISBNs
978-3-03-489901-7, 978-3-03-489088-5
Authors

R Voellmy, Voellmy, R., R. Voellmy

Abstract

Heat shock protein gene expression is enhanced by proteotoxic stress, i.e., by conditions favoring protein unfolding. This upregulation of heat shock protein genes is mediated by heat shock transcription factor HSF1. A mechanism, the details of which are still elusive, senses adverse conditions and causes HSF1 to oligomerize and to acquire DNA-binding ability. The DNA-binding form of HSF1 then undergoes further conformational changes that render it transcriptionally competent. The current model in which heat shock protein 70 acts both as sensor of stress and as negative regulator of HSF1 oligomerization as well as alternative models involving additional protein factors are discussed.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 44%
Researcher 2 22%
Student > Doctoral Student 1 11%
Student > Bachelor 1 11%
Unknown 1 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 3 33%
Environmental Science 1 11%
Biochemistry, Genetics and Molecular Biology 1 11%
Pharmacology, Toxicology and Pharmaceutical Science 1 11%
Nursing and Health Professions 1 11%
Other 1 11%
Unknown 1 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 May 2023.
All research outputs
#7,453,827
of 22,787,797 outputs
Outputs from EXS
#28
of 94 outputs
Outputs of similar age
#16,764
of 79,181 outputs
Outputs of similar age from EXS
#1
of 5 outputs
Altmetric has tracked 22,787,797 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 94 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.7. This one has gotten more attention than average, scoring higher than 50% of its peers.
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We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them