| Chapter title |
Th17 Differentiation and Their Pro-inflammation Function.
|
|---|---|
| Chapter number | 5 |
| Book title |
T Helper Cell Differentiation and Their Function
|
| Published in |
Advances in experimental medicine and biology, September 2014
|
| DOI | 10.1007/978-94-017-9487-9_5 |
| Pubmed ID | |
| Book ISBNs |
978-9-40-179486-2, 978-9-40-179487-9
|
| Authors |
Song X, Gao H, Qian Y, Xinyang Song, Hanchao Gao, Youcun Qian, Song, Xinyang, Gao, Hanchao, Qian, Youcun |
| Abstract |
CD4(+) T helper cells are classical but constantly reinterpreted T-cell subset, playing critical roles in a diverse range of inflammatory responses or diseases. Depending on the cytokines they release and the immune responses they mediate, CD4(+) T cells are classically divided into two major cell populations: Th1 and Th2 cells. However, recent studies challenged this Th1/Th2 paradigm by discovering several T-helper cell subsets with specific differentiation program and functions, including Th17 cells, Treg cells, and Tfh cells. In this chapter, we summarize the current understanding and recent progresses on the Th17 lineage differentiation and its effector impacts on variety of inflammatory responses or disease pathogenesis. |
X Demographics
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Demographic breakdown
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Mendeley readers
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| Other | 1 | 3% |
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