Chapter title |
Antimicrobial photodynamic inactivation and photodynamic therapy for infections.
|
---|---|
Chapter number | 12 |
Book title |
Photodynamic Therapy
|
Published in |
Methods in molecular biology, February 2015
|
DOI | 10.1007/978-1-60761-697-9_12 |
Pubmed ID | |
Book ISBNs |
978-1-60761-696-2, 978-1-60761-697-9
|
Authors |
Liyi Huang, Tianhong Dai, Michael R. Hamblin, Huang L, Dai T, Hamblin MR, Huang, Liyi, Dai, Tianhong, Hamblin, Michael R. |
Abstract |
Photodynamic therapy (PDT) was initially discovered over 100 years ago by its ability to kill microorganisms, but its use to treat infections clinically has not been much developed. However, the present relentless increase in antibiotic resistance worldwide and the emergence of strains that are resistant to all known antibiotics has stimulated research into novel antimicrobial strategies such as PDT that are thought to be unlikely to lead to the development of resistance. In this chapter we will cover the use of PDT to kill pathogenic microbial cells in vitro and describe a mouse model of localized infection and its treatment by PDT without causing excessive damage to the host tissue. |
Mendeley readers
Geographical breakdown
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Poland | 2 | 2% |
Portugal | 1 | <1% |
Unknown | 123 | 98% |
Demographic breakdown
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Student > Master | 24 | 19% |
Researcher | 17 | 13% |
Student > Ph. D. Student | 17 | 13% |
Student > Bachelor | 15 | 12% |
Student > Doctoral Student | 8 | 6% |
Other | 19 | 15% |
Unknown | 26 | 21% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 17 | 13% |
Biochemistry, Genetics and Molecular Biology | 13 | 10% |
Immunology and Microbiology | 7 | 6% |
Other | 21 | 17% |
Unknown | 32 | 25% |