You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Attention Score in Context
Chapter title |
Systemic delivery of synthetic siRNAs.
|
---|---|
Chapter number | 6 |
Book title |
RNA Therapeutics
|
Published in |
Methods in molecular biology, February 2010
|
DOI | 10.1007/978-1-60761-657-3_6 |
Pubmed ID | |
Book ISBNs |
978-1-60761-656-6, 978-1-60761-657-3
|
Authors |
Sørensen DR, Sioud M, Sørensen, Dag R., Sioud, Mouldy, Dag R. Sørensen, Mouldy Sioud |
Abstract |
RNA interference is a biological process for gene silencing that can be harnessed for the development of new drugs. However, a major obstacle to the use of small interfering RNAs (siRNAs) as therapeutics is their delivery across the plasma membrane of cells in vivo. A range of solutions for this challenge have been described, including cationic lipids, high-pressure injection, viral vectors, and chemical modifications of the siRNAs. This chapter describes cationic lipid delivery of siRNAs to adult mice. |
Mendeley readers
The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 8 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 2 | 25% |
Student > Ph. D. Student | 2 | 25% |
Student > Doctoral Student | 1 | 13% |
Student > Master | 1 | 13% |
Researcher | 1 | 13% |
Other | 1 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 6 | 75% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 13% |
Medicine and Dentistry | 1 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 August 2020.
All research outputs
#7,452,489
of 22,783,848 outputs
Outputs from Methods in molecular biology
#2,316
of 13,094 outputs
Outputs of similar age
#49,022
of 165,411 outputs
Outputs of similar age from Methods in molecular biology
#34
of 127 outputs
Altmetric has tracked 22,783,848 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,094 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 165,411 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 127 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.