Chapter title |
Rotavirus proteins: structure and assembly.
|
---|---|
Chapter number | 7 |
Book title |
Reoviruses: Entry, Assembly and Morphogenesis
|
Published in |
Current topics in microbiology and immunology, August 2006
|
DOI | 10.1007/3-540-30773-7_7 |
Pubmed ID | |
Book ISBNs |
978-3-54-030772-3, 978-3-54-030773-0
|
Authors |
Pesavento JB, Crawford SE, Estes MK, Prasad BV, J. B. Pesavento, S. E. Crawford, M. K. Estes, B. V. Venkataram Prasad, Pesavento, J. B., Crawford, S. E., Estes, M. K., Venkataram Prasad, B. V. |
Abstract |
Rotavirus is a major pathogen of infantile gastroenteritis. It is a large and complex virus with a multilayered capsid organization that integrates the determinants of host specificity, cell entry, and the enzymatic functions necessary for endogenous transcription of the genome that consists of 11 dsRNA segments. These segments encode six structural and six nonstructural proteins. In the last few years, there has been substantial progress in our understanding of both the structural and functional aspects of a variety of molecular processes involved in the replication of this virus. Studies leading to this progress using of a variety of structural and biochemical techniques including the recent application of RNA interference technology have uncovered several unique and intriguing features related to viral morphogenesis. This review focuses on our current understanding of the structural basis of the molecular processes that govern the replication of rotavirus. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
South Africa | 2 | 1% |
United Kingdom | 2 | 1% |
United States | 2 | 1% |
Brazil | 1 | <1% |
Canada | 1 | <1% |
Colombia | 1 | <1% |
China | 1 | <1% |
Mexico | 1 | <1% |
Unknown | 189 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 47 | 24% |
Student > Bachelor | 25 | 13% |
Researcher | 20 | 10% |
Student > Ph. D. Student | 19 | 10% |
Student > Postgraduate | 17 | 9% |
Other | 31 | 16% |
Unknown | 41 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 64 | 32% |
Biochemistry, Genetics and Molecular Biology | 38 | 19% |
Immunology and Microbiology | 18 | 9% |
Medicine and Dentistry | 13 | 7% |
Engineering | 9 | 5% |
Other | 16 | 8% |
Unknown | 42 | 21% |