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From Innate Immunity to Immunological Memory

Overview of attention for book
Attention for Chapter 3: Helper T cell-regulated B cell immunity.
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12 Wikipedia pages

Citations

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53 Mendeley
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Chapter title
Helper T cell-regulated B cell immunity.
Chapter number 3
Book title
From Innate Immunity to Immunological Memory
Published in
Current topics in microbiology and immunology, October 2006
DOI 10.1007/3-540-32636-7_3
Pubmed ID
Book ISBNs
978-3-54-032635-9, 978-3-54-032636-6
Authors

McHeyzer-Williams LJ, Malherbe LP, McHeyzer-Williams MG, McHeyzer-Williams, L. J., Malherbe, L. P., McHeyzer-Williams, M. G., L. J. McHeyzer-Williams, L. P. Malherbe, M. G. McHeyzer-Williams

Abstract

In this review, we will discuss the cascade of cellular and molecular events in the immune response to protein antigens that regulate the development of high-affinity B cell memory. The behavior of antigen-experienced pMHCII+ dendritic cells DCs and the dynamics of their interaction with specific T-helper (Th) cells define the first developmental checkpoint for adaptive immunity in vivo. Recent studies provide insight into the basis of Th cell clonal selection and the requirements and consequences of antigen priming in this responsive Th cell compartment. Antigen-specific Th cells expand to become the cognate regulators of effector B cell responses and initiators of the germinal center reaction and memory B cell development. We will discuss the development and role of these diverse mixtures of antigen-specific B cells in the control of B cell memory and long-term humoral immunity that underpin effective protein vaccination.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Italy 1 2%
Belgium 1 2%
Saudi Arabia 1 2%
Unknown 49 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 26%
Student > Master 8 15%
Student > Bachelor 8 15%
Researcher 6 11%
Student > Doctoral Student 3 6%
Other 9 17%
Unknown 5 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 38%
Immunology and Microbiology 8 15%
Medicine and Dentistry 8 15%
Biochemistry, Genetics and Molecular Biology 3 6%
Chemistry 3 6%
Other 6 11%
Unknown 5 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 February 2023.
All research outputs
#7,680,234
of 23,372,207 outputs
Outputs from Current topics in microbiology and immunology
#206
of 687 outputs
Outputs of similar age
#23,788
of 67,863 outputs
Outputs of similar age from Current topics in microbiology and immunology
#4
of 7 outputs
Altmetric has tracked 23,372,207 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 687 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 67,863 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.