Chapter title |
Construction of Escherichia Coli Cell Factories for Production of Organic Acids and Alcohols.
|
---|---|
Chapter number | 294 |
Book title |
Bioreactor Engineering Research and Industrial Applications I
|
Published in |
Advances in biochemical engineering biotechnology, January 2015
|
DOI | 10.1007/10_2014_294 |
Pubmed ID | |
Book ISBNs |
978-3-66-249159-1, 978-3-66-249161-4
|
Authors |
Pingping Liu, Xinna Zhu, Zaigao Tan, Xueli Zhang, Yanhe Ma, Liu P, Zhu X, Tan Z, Zhang X, Ma Y, Liu, Pingping, Zhu, Xinna, Tan, Zaigao, Zhang, Xueli, Ma, Yanhe |
Abstract |
: Production of bulk chemicals from renewable biomass has been proved to be sustainable and environmentally friendly. Escherichia coli is the most commonly used host strain for constructing cell factories for production of bulk chemicals since it has clear physiological and genetic characteristics, grows fast in minimal salts medium, uses a wide range of substrates, and can be genetically modified easily. With the development of metabolic engineering, systems biology, and synthetic biology, a technology platform has been established to construct E. coli cell factories for bulk chemicals production. In this chapter, we will introduce this technology platform, as well as E. coli cell factories successfully constructed for production of organic acids and alcohols. |
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